| Literature DB >> 11479537 |
N Morishita1, K Yamazaki, J Ninomiya, T Hamaguchi, Y Sei, I Takiuchi.
Abstract
We report a case of lymphocutaneous sporotrichosis in a 69-year old man who had nodular-ulcerated lesions on the right hand and forearm. Small nodules remained on the right hand after 8 weeks of 0.5 g daily treatment with potassium iodide. Alternatively, terbinafine therapy (125 mg/day) resulted in healing with atrophic scars after 9 weeks without side effects. We reviewed 67 patients of cutaneous sporotrichosis in Japan from 1993 to 1999. Those cure rates (and mean durations of treatments in parentheses) are 90.9% (8.1 weeks) with potassium iodide, 86.6% (12.6 weeks) with itraconazole (100 mg/day) and 71.4% (12.8 weeks) with terbinafine (125 mg/day) treatments, respectively. These results lead us to consider a daily dose of 250 mg as more appropriate for terbinafine.Entities:
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Year: 2001 PMID: 11479537 DOI: 10.3314/jjmm.42.149
Source DB: PubMed Journal: Nihon Ishinkin Gakkai Zasshi ISSN: 0916-4804