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Literature DB >> 1147903

The conversion of cholest-5-en-3beta-ol into cholest-7-en-3beta-ol by the echinoderms Asterias rubens and Solaster papposus.

Abstract

1. The echinoderms Asterias rubens and Solaster papposus (Class Asteroidea) metabolize injected [4(-14)C]cholest-5-en-3beta-ol to produce labelled 5alpha-cholestan-3beta-ol and 5alpha-cholest-7-en-3beta-ol. 2. Conversion of 5alpha-[4(-14)C]cholestan-3beta-ol into 5alpha-cholest-7-en-3beta-ol was demonstrated in A. Rubens. 3. Incubations of A. rubens with [4(-14)C]cholest-4-en-3-one resulted in the production of labelled 5alpha-cholestan-3-one, 5alpha-cholestan-3beta-ol and 5alpha-cholest-7-en-3beta-ol. 4. [4(-14)C]Sitosterol was metabolized by A. rubens to give 5alpha-stigmastan-3beta-ol and 5alpha-stigmast-7-en-3beta-ol. 5. The significance of these results in relation to the presence of alpha7 sterols in starfish is discussed.

Entities: Chemical Species

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Year: 1975 PMID： 1147903 PMCID： PMC1165273 DOI： 10.1042/bj1460035

Source DB: PubMed Journal: Biochem J ISSN： 0264-6021 Impact factor: 3.857

8 in total

Review 4. The sterols of echinoderms.

Authors: L J Goad; I Rubinstein; A G Smith
Journal: Proc R Soc Lond B Biol Sci Date: 1972-02-15

3 in total

1. Sterol biosynthesis in the echinoderm Asterias rubens.

Authors: A G Smith; L J Goad
Journal: Biochem J Date: 1975-01 Impact factor: 3.857

2. Expression and chloroplast targeting of cholesterol oxidase in transgenic tobacco plants.

Authors: D R Corbin; R J Grebenok; T E Ohnmeiss; J T Greenplate; J P Purcell
Journal: Plant Physiol Date: 2001-07 Impact factor: 8.340

3. The substrate specificity and stereochemistry, reversibility and inhibition of the 3-oxo steroid delta 4-delta 5-isomerase component of cholesterol oxidase.

Authors: A G Smith; C J Brooks
Journal: Biochem J Date: 1977-10-01 Impact factor: 3.857

3 in total

The conversion of cholest-5-en-3beta-ol into cholest-7-en-3beta-ol by the echinoderms Asterias rubens and Solaster papposus.

1. Conversion of 5-alpha-cholestan-3-beta-ol to delta-7-5-alpha-cholesten-3-beta-ol in cockroaches.

2. Marine sterols. 6. Sterol biosynthesis in molluscs and echinoderms.

3. Conversion of cholestanol to delta7-cholestenol by the German cockroach.

Review 4. The sterols of echinoderms.

5. Some aspects of the sterol metabolism in the echinoderm Asterias rubens.

6. Steroids from starfish.

7. Sterol biosynthesis by the sea urchin Echinus esculentus.

8. The sterols of the echinoderm Asterias rubens.

1. Sterol biosynthesis in the echinoderm Asterias rubens.

2. Expression and chloroplast targeting of cholesterol oxidase in transgenic tobacco plants.

3. The substrate specificity and stereochemistry, reversibility and inhibition of the 3-oxo steroid delta 4-delta 5-isomerase component of cholesterol oxidase.