Literature DB >> 11477214

Interleukin-18 in human milk.

Y Takahata1, H Takada, A Nomura, K Ohshima, H Nakayama, T Tsuda, H Nakano, T Hara.   

Abstract

We analyzed IL-18 levels of human milk. Colostrum contained significantly higher levels of IL-18 compared with early milk and mature milk. By stepwise multiple linear regression analysis, preterm delivery and pregnancy complications of mothers significantly correlated with high levels of IL-18 in human milk (p = 0.0007 and 0.0018, respectively). There was a significant correlation between the levels of IL-18 and soluble Fas ligand in colostrum (p = 0.0003). IL-18 was detected in actively secreting epithelial cells in lactating mammary gland by immunohistochemical staining. These results suggest that IL-18 in colostrum plays an important role in host defense of high-risk neonates.

Entities:  

Mesh：

Substances：

Year:  2001        PMID： 11477214     DOI： 10.1203/00006450-200108000-00017

Source DB:  PubMed          Journal:  Pediatr Res        ISSN： 0031-3998            Impact factor:   3.756


  10 in total

Review 1.  The utility of breastmilk for genetic or genomic studies: a systematic review.

Authors:  Kelley L Baumgartel; Yvette P Conley
Journal:  Breastfeed Med       Date:  2012-12-21       Impact factor: 1.817

Review 2.  New concepts of microbial translocation in the neonatal intestine: mechanisms and prevention.

Authors:  Michael P Sherman
Journal:  Clin Perinatol       Date:  2010-09       Impact factor: 3.430

Review 3.  Cytokines and growth factors in the developing intestine and during necrotizing enterocolitis.

Authors:  Krishnan MohanKumar; Kopperuncholan Namachivayam; Thao T B Ho; Benjamin A Torres; Robin K Ohls; Akhil Maheshwari
Journal:  Semin Perinatol       Date:  2016-11-07       Impact factor: 3.300

Review 4.  Protective effects of amniotic fluid in the setting of necrotizing enterocolitis.

Authors:  Soham Dasgupta; Sunil Kumar Jain
Journal:  Pediatr Res       Date:  2017-07-05       Impact factor: 3.756

5.  TGF-β2, a protective intestinal cytokine, is abundant in maternal human milk and human-derived fortifiers but not in donor human milk.

Authors:  Aaron A Reeves; Marney C Johnson; Margarita M Vasquez; Akhil Maheshwari; Cynthia L Blanco
Journal:  Breastfeed Med       Date:  2013-07-19       Impact factor: 1.817

6.  Microarray analysis of human milk cells: persistent high expression of osteopontin during the lactation period.

Authors:  T Nagatomo; S Ohga; H Takada; A Nomura; S Hikino; M Imura; K Ohshima; T Hara
Journal:  Clin Exp Immunol       Date:  2004-10       Impact factor: 4.330

7.  Interleukin 7 from maternal milk crosses the intestinal barrier and modulates T-cell development in offspring.

Authors:  Richard Aspinall; Andrew M Prentice; Pa Tamba Ngom
Journal:  PLoS One       Date:  2011-06-30       Impact factor: 3.240

8.  Colostrum and Mature Human Milk of Women from London, Moscow, and Verona: Determinants of Immune Composition.

Authors:  Daniel Munblit; Marina Treneva; Diego G Peroni; Silvia Colicino; LiYan Chow; Shobana Dissanayeke; Priya Abrol; Shreya Sheth; Alexander Pampura; Attilio L Boner; Donna T Geddes; Robert J Boyle; John O Warner
Journal:  Nutrients       Date:  2016-11-03       Impact factor: 5.717

Review 9.  Human Milk and Allergic Diseases: An Unsolved Puzzle.

Authors:  Daniel Munblit; Diego G Peroni; Alba Boix-Amorós; Peter S Hsu; Belinda Van't Land; Melvin C L Gay; Anastasia Kolotilina; Chrysanthi Skevaki; Robert J Boyle; Maria Carmen Collado; Johan Garssen; Donna T Geddes; Ralph Nanan; Carolyn Slupsky; Ganesa Wegienka; Anita L Kozyrskyj; John O Warner
Journal:  Nutrients       Date:  2017-08-17       Impact factor: 5.717

10.  Human Milk Oligosaccharide Supplementation Affects Intestinal Barrier Function and Microbial Composition in the Gastrointestinal Tract of Young Sprague Dawley Rats.

Authors:  Faye Chleilat; Teja Klancic; Kyle Ma; Alana Schick; Jodi E Nettleton; Raylene A Reimer
Journal:  Nutrients       Date:  2020-05-25       Impact factor: 5.717
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.