| Literature DB >> 1147599 |
M Nakae, M Inoue, S Mitsuhashi.
Abstract
Ten strains of beta-hemolytic streptococci were tested for elimination of resistance to macrolide antibiotics, tetracycline, and chloramphenicol. Six of the strains lost resistance after cultivation at 41 C or addition of acriflavine (0.2 mug/ml). These results suggest that determinants governing resistance to these antibiotics are located on extrachromosomal genetic elements (plasmids) that are widely distributed in streptococci.Entities:
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Year: 1975 PMID: 1147599 PMCID: PMC429211 DOI: 10.1128/AAC.7.5.719
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191