Literature DB >> 11475141

Advancement flap plasty for the closure of anal and recto-vaginal fistulas in Crohn's disease.

F Penninckx1, A D'Hoore, L Filez.   

Abstract

The management of anal fistulas in patients with IBD continues to be extremely challenging and, indeed, somewhat frustrating. Despite a global closure rate of about 75%, all patients should be informed about the risk of infection, early failure, eventual temporary disfunctioning stoma and the possibility of late recurrence (about 15%). Closure of a RVF in Crohn's disease should not be considered an easy undertaking, especially in patients with several Crohn localisations. The technique can be adapted to the local situation. Construction of a temporary stoma is not mandatory. However, stoma construction seems to be beneficial when extensive perianal or recto-vaginal dissection including eventual tissue interposition is required. Advancement flaps are an attractive surgical alternative for the management of all anal transsphincteric fistulas, also in Crohn's disease, because sphincter architecture and function are well preserved. Improved medical treatment and the changed approach from conservative to reparative surgery may well have resulted in a decreased need or at least in a delay of the need for a proctectomy. Although the surgical principles of advancement flap techniques are sound, these techniques have not been used for many decades. Skills needed, problematic approach, suboptimal quality of local tissues have contributed to its selective use and to the absence of prospective randomised studies.

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Mesh:

Year:  2001        PMID: 11475141

Source DB:  PubMed          Journal:  Acta Gastroenterol Belg        ISSN: 1784-3227            Impact factor:   1.316


  4 in total

1.  Autologous stem cell transplantation for treatment of rectovaginal fistula in perianal Crohn's disease: a new cell-based therapy.

Authors:  Damian García-Olmo; Mariano García-Arranz; Lourdes Gómez García; Eduardo Serna Cuellar; Ignacio Fernández Blanco; Luis Asensio Prianes; José Antonio Rodríguez Montes; Francisca Lima Pinto; Dolores Herreros Marcos; Luis García-Sancho
Journal:  Int J Colorectal Dis       Date:  2003-05-20       Impact factor: 2.571

2.  Analysis of function and predictors of failure in women undergoing repair of Crohn's related rectovaginal fistula.

Authors:  Galal El-Gazzaz; Tracy Hull; Emilio Mignanelli; Jeffery Hammel; Brook Gurland; Massarat Zutshi
Journal:  J Gastrointest Surg       Date:  2010-03-16       Impact factor: 3.452

3.  Adipose-derived stem cells in Crohn's rectovaginal fistula.

Authors:  D García-Olmo; D Herreros; P De-La-Quintana; H Guadalajara; J Trébol; T Georgiev-Hristov; M García-Arranz
Journal:  Case Rep Med       Date:  2010-03-07

4.  Perioperative adjuvant therapy with infliximab in complicated anal Crohn's disease.

Authors:  M Kraemer; A Kirschmeier; T Marth
Journal:  Int J Colorectal Dis       Date:  2008-06-14       Impact factor: 2.571

  4 in total

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