| Literature DB >> 11474959 |
Abstract
Muscle oxidative function appears to decline with aging, and evidence suggests that this is related to reduced synthesis of mitochondrial and other muscle proteins. Causes for these events may include mtDNA damage or reduced mtDNA copy numbers, reduced oxidative enzyme activities and ATP production, and increased proton leak.Entities:
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Year: 2001 PMID： 11474959 DOI： 10.1097/00003677-200107000-00006
Source DB: PubMed Journal: Exerc Sport Sci Rev ISSN： 0091-6331 Impact factor: 6.230