Literature DB >> 11474740

Immunomodulative effects of aflatoxins and selenium on human natural killer cells.

G Methenitou1, C Maravelias, S Athanaselis, A Dona, A Koutselinis.   

Abstract

The possible immunomodulative effects of aflatoxin B1 and selenium (as sodium selenite) at concentrations lower than 5.10(-11) M or 0.05ppb and 10(-5) M, respectively on natural killer (NK) cells from healthy volunteers were evaluated by a 51Cr release natural killer assay. Aflatoxin B1 and selenium separately had an immunosuppressive effect on NK cell activity. When they were studied in combination, they caused a statistically significant increase of the cytotoxic activity of NK cells in the presence of the lowest concentrations of aflatoxin B1 (0.005ppb) and of sodium selenite (10(-8)M).

Entities:  

Mesh：

Substances：

Year:  2001        PMID： 11474740

Source DB:  PubMed          Journal:  Vet Hum Toxicol        ISSN： 0145-6296


  6 in total

1.  Dietary selenium affects intestinal development of Eimeria papillata in mice.

Authors:  Mohamed A Dkhil; Abdel Azeem S Abdel-Baki; Frank Wunderlich; Helmut Sies; Saleh Al-Quraishy
Journal:  Parasitol Res       Date:  2013-11-13       Impact factor: 2.289

2.  A case-control study of the risk of cutaneous melanoma associated with three selenium exposure indicators.

Authors:  Marco Vinceti; Catherine M Crespi; Carlotta Malagoli; Ilaria Bottecchi; Angela Ferrari; Sabina Sieri; Vittorio Krogh; Dorothea Alber; Margherita Bergomi; Stefania Seidenari; Giovanni Pellacani
Journal:  Tumori       Date:  2012 May-Jun

3.  Pathological Impairment, Cell Cycle Arrest and Apoptosis of Thymus and Bursa of Fabricius Induced by Aflatoxin-Contaminated Corn in Broilers.

Authors:  Xi Peng; Shiping Bai; Xuemei Ding; Keying Zhang
Journal:  Int J Environ Res Public Health       Date:  2017-01-13       Impact factor: 3.390

Review 4.  Chronic and Acute Toxicities of Aflatoxins: Mechanisms of Action.

Authors:  Noreddine Benkerroum
Journal:  Int J Environ Res Public Health       Date:  2020-01-08       Impact factor: 3.390

Review 5.  Metabolic Disruption by Naturally Occurring Mycotoxins in Circulation: A Focus on Vascular and Bone Homeostasis Dysfunction.

Authors:  Amir Mohammad Malvandi; Sara Shahba; Jalil Mehrzad; Giovanni Lombardi
Journal:  Front Nutr       Date:  2022-06-24

6.  Transcriptional Profiling of Aflatoxin B1-Induced Oxidative Stress and Inflammatory Response in Macrophages.

Authors:  Jinglin Ma; Yanrong Liu; Yongpeng Guo; Qiugang Ma; Cheng Ji; Lihong Zhao
Journal:  Toxins (Basel)       Date:  2021-06-04       Impact factor: 4.546
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.