Literature DB >> 11474739

Dimethyl sulfoxide: recent pharmacological and toxicological research.

B H Ali1.   

Abstract

A survey of the literature published in the past 2 decades on the basic pharmacology, therapeutic uses and toxicity of dimethyl sulfoxide (DMSO) is presented. A salient pharmacological action of DMSO is its ability to scavenge oxygen-free radicals implicated in xenobiotic-induced tissue damages when given before, during or several hours after the tissue insult. More trials with DMSO in diseases and conditions caused by oxygen-free radicals are warranted.

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Year:  2001        PMID： 11474739

Source DB:  PubMed          Journal:  Vet Hum Toxicol        ISSN： 0145-6296


  4 in total

1.  A screen of pharmaceutical drugs for their ability to cause short-term morbidity and mortality in the common bed bug, Cimex lectularius L.

Authors:  Johnathan M Sheele; Gale E Ridge; Wenjing Du; Nikhil Mallipeddi; Mayur Vallabhaneni
Journal:  Parasitol Res       Date:  2017-08-03       Impact factor: 2.289

2.  Pharmacokinetics and metabolism of a selective androgen receptor modulator in rats: implication of molecular properties and intensive metabolic profile to investigate ideal pharmacokinetic characteristics of a propanamide in preclinical study.

Authors:  Di Wu; Zengru Wu; Jun Yang; Vipin A Nair; Duane D Miller; James T Dalton
Journal:  Drug Metab Dispos       Date:  2005-12-28       Impact factor: 3.922

3.  Progeroid syndrome patients with ZMPSTE24 deficiency could benefit when treated with rapamycin and dimethylsulfoxide.

Authors:  Baris Akinci; Shireesha Sankella; Christopher Gilpin; Keiichi Ozono; Abhimanyu Garg; Anil K Agarwal
Journal:  Cold Spring Harb Mol Case Stud       Date:  2017-01

4.  Out of control: The need for standardised solvent approaches and data reporting in antibiofilm assays incorporating dimethyl-sulfoxide (DMSO).

Authors:  Kate Summer; Jessica Browne; Matthijs Hollanders; Kirsten Benkendorff
Journal:  Biofilm       Date:  2022-08-17
  4 in total

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