Literature DB >> 11473835

Th1- and Th2-cell commitment during infectious disease: asymmetry in divergent pathways.

D Jankovic1, Z Liu, W C Gause.   

Abstract

The development of T helper 1 (Th1) versus Th2 cells is a major branch point in the immune response. It is an important determinant of whether the response to an infectious pathogen will lead to protection of the host or dissemination of the disease. Recent studies have suggested that this process is governed by distinct sets of signals provided by dendritic cells upon interactions with specific infectious agents. A model is proposed that links together the pathogen, the innate response and Th-cell polarization.

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Year:  2001        PMID: 11473835     DOI: 10.1016/s1471-4906(01)01975-5

Source DB:  PubMed          Journal:  Trends Immunol        ISSN: 1471-4906            Impact factor:   16.687


  56 in total

1.  Involvement of fractalkine/CX3CL1 expression by dendritic cells in the enhancement of host immunity against Legionella pneumophila.

Authors:  Toshiaki Kikuchi; Sita Andarini; Hong Xin; Kazunori Gomi; Yutaka Tokue; Yasuo Saijo; Tasuku Honjo; Akira Watanabe; Toshihiro Nukiwa
Journal:  Infect Immun       Date:  2005-09       Impact factor: 3.441

2.  Early cytokine production is associated with protection from murine cerebral malaria.

Authors:  Andrew J Mitchell; Anna M Hansen; Leia Hee; Helen J Ball; Sarah M Potter; John C Walker; Nicholas H Hunt
Journal:  Infect Immun       Date:  2005-09       Impact factor: 3.441

Review 3.  A biological context for the self-nonself discrimination and the regulation of effector class by the immune system.

Authors:  Melvin Cohn
Journal:  Immunol Res       Date:  2005       Impact factor: 2.829

Review 4.  From the Th1/Th2 paradigm towards a Toll-like receptor/T-helper bias.

Authors:  Mihai G Netea; Jos W M Van der Meer; Roger P Sutmuller; Gosse J Adema; Bart-Jan Kullberg
Journal:  Antimicrob Agents Chemother       Date:  2005-10       Impact factor: 5.191

Review 5.  The host immune dynamics of pneumococcal colonization: implications for novel vaccine development.

Authors:  M Nadeem Khan; Michael E Pichichero
Journal:  Hum Vaccin Immunother       Date:  2014       Impact factor: 3.452

6.  Both free-living and parasitic nematodes induce a characteristic Th2 response that is dependent on the presence of intact glycans.

Authors:  Salah Tawill; Laetitia Le Goff; Fahimeda Ali; Mark Blaxter; Judith E Allen
Journal:  Infect Immun       Date:  2004-01       Impact factor: 3.441

7.  Formononetin, a phyto-oestrogen, and its metabolites up-regulate interleukin-4 production in activated T cells via increased AP-1 DNA binding activity.

Authors:  Jin Park; Seung H Kim; Daeho Cho; Tae S Kim
Journal:  Immunology       Date:  2005-09       Impact factor: 7.397

Review 8.  Persistent Infection and Long-Term Carriage of Typhoidal and Nontyphoidal Salmonellae.

Authors:  Ohad Gal-Mor
Journal:  Clin Microbiol Rev       Date:  2018-11-28       Impact factor: 26.132

9.  Fasciola hepatica: identification of CD4+ T-helper epitopes from the 11.5 kDa saposin-like protein SAP-2 using synthetic peptides.

Authors:  Ana M Espino; Daricel Torres; Adelaida Morales; Bonnibel Delgado; Julia Quetel; Antonio Osuna
Journal:  Exp Parasitol       Date:  2007-03-27       Impact factor: 2.011

10.  Senescent BALB/c mice are able to develop resistance to Leishmania major infection.

Authors:  Jan Ehrchen; Anca Sindrilaru; Stephan Grabbe; Frank Schönlau; Christian Schlesiger; Clemens Sorg; Karin Scharffetter-Kochanek; Cord Sunderkötter
Journal:  Infect Immun       Date:  2004-09       Impact factor: 3.441

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