| Literature DB >> 11473206 |
M Ohta1, Y Tokuda, Y Suzuki, M Kubota, H Makuuchi, T Tajima, S Nasu, Y Suzuki, S Yasuda, A Shohtsu.
Abstract
The purpose of this study was to determine the potential role of positron emission tomography (PET) using 2-[18F]-fluoro-2-deoxy-D-glucose (FDG) for the evaluation of bony metastasis compared with 99Tcm-methylene diphosphonate (99Tcm-MDP) bone scintigraphy in patients with breast cancer. Fifty-one female patients with breast cancer who had PET together with a bone scan within 1 month between September 1994 and March 1997 were included in this study. The median age was 49 years (range 29-79 years). The sensitivity, specificity and accuracy of the bone scan were 77.7%, 80.9% and 80.3%, respectively. On the other hand, for the detection of bone metastases PET had a sensitivity, specificity and accuracy of 77.7%, 97.6% and 94.1%, respectively. In the diagnosis of bony metastasis derived from breast cancer, FDG-PET was statistically superior to bone scintigraphy in its specificity. In conclusion, FDG-PET appears to be a powerful tool not only in the diagnosis of the primary lesion and soft tissue metastasis, but also in the diagnosis of bony metastasis among patients with breast cancer.Entities:
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Year: 2001 PMID： 11473206 DOI： 10.1097/00006231-200108000-00005
Source DB: PubMed Journal: Nucl Med Commun ISSN： 0143-3636 Impact factor: 1.690