Literature DB >> 11472827

The formulation of an effective topical antibacterial product containing Ocimum gratissimum leaf essential oil.

L O Orafidiya1, A O Oyedele, A O Shittu, A A Elujoba.   

Abstract

The antibacterial potential of Ocimum gratissimum essential oil was explored. Liquid and semisolid formulations of the oil were designed in a variety of bases for topical antiseptic medication. The products were evaluated by agar diffusion assay against type strains and clinical isolates from boil, wound and pimples. Remarkable antibacterial effects, higher than those of commercial antiseptic products, were demonstrated at 2% Ocimum oil concentration in some bases. The properties of base into which the oil was incorporated affected its activity. It was more effective in hydrophilic bases than in lipophilic bases. Solubilization and microemulsification grossly reduced its activity.

Entities:  

Mesh：

Substances：

Year:  2001        PMID： 11472827     DOI： 10.1016/s0378-5173(01)00764-5

Source DB:  PubMed          Journal:  Int J Pharm        ISSN： 0378-5173            Impact factor:   5.875


  8 in total

Review 1.  Natural compounds containing mouthrinses in the management of dental plaque and gingivitis: a systematic review.

Authors:  Yong Chen; Ricky W K Wong; Colman McGrath; Urban Hagg; C Jayampath Seneviratne
Journal:  Clin Oral Investig       Date:  2013-07-17       Impact factor: 3.573

Review 2.  Calamintha nepeta (L.) Savi and its Main Essential Oil Constituent Pulegone: Biological Activities and Chemistry.

Authors:  Mijat Božović; Rino Ragno
Journal:  Molecules       Date:  2017-02-14       Impact factor: 4.411

3.  Methanol extract of Ocimum gratissimum protects murine peritoneal macrophages from nicotine toxicity by decreasing free radical generation, lipid and protein damage and enhances antioxidant protection.

Authors:  Santanu Kar Mahapatra; Subhankari Prasad Chakraborty; Subhasis Das; Somenath Roy
Journal:  Oxid Med Cell Longev       Date:  2009 Sep-Oct       Impact factor: 6.543

4.  Wound healing activity of Hemidesmus indicus formulation.

Authors:  S Ganesan; S Parasuraman; S Uma Maheswaran; N Gnanasekar
Journal:  J Pharmacol Pharmacother       Date:  2012-01

Review 5.  Early state research on antifungal natural products.

Authors:  Melyssa Negri; Tânia P Salci; Cristiane S Shinobu-Mesquita; Isis R G Capoci; Terezinha I E Svidzinski; Erika Seki Kioshima
Journal:  Molecules       Date:  2014-03-07       Impact factor: 4.411

6.  The Antimicrobial Effect of Melissa officinalis L. Essential Oil on Vibrio parahaemolyticus: Insights Based on the Cell Membrane and External Structure.

Authors:  Huijie Yu; Juxin Pei; Weiqiang Qiu; Jun Mei; Jing Xie
Journal:  Front Microbiol       Date:  2022-03-10       Impact factor: 5.640

7.  Enrichment, development, and assessment of Indian basil oil based antiseptic cream formulation utilizing hydrophilic-lipophilic balance approach.

Authors:  Narayan Prasad Yadav; Jaya Gopal Meher; Neelam Pandey; Suaib Luqman; Kuldeep Singh Yadav; Debabrata Chanda
Journal:  Biomed Res Int       Date:  2013-07-31       Impact factor: 3.411

Review 8.  Recent Advances in the Application of Antibacterial Complexes Using Essential Oils.

Authors:  Tae Jin Cho; Sun Min Park; Hary Yu; Go Hun Seo; Hye Won Kim; Sun Ae Kim; Min Suk Rhee
Journal:  Molecules       Date:  2020-04-10       Impact factor: 4.411
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.