Literature DB >> 11470609

Polymers in drug delivery.

O Pillai1, R Panchagnula.   

Abstract

Advances in polymer science have led to the development of several novel drug-delivery systems. A proper consideration of surface and bulk properties can aid in the designing of polymers for various drug-delivery applications. Biodegradable polymers find widespread use in drug delivery as they can be degraded to non-toxic monomers inside the body. Novel supramolecular structures based on polyethylene oxide copolymers and dendrimers are being intensively researched for delivery of genes and macromolecules. Hydrogels that can respond to a variety of physical, chemical and biological stimuli hold enormous potential for design of closed-loop drug-delivery systems. Design and synthesis of novel combinations of polymers will expand the scope of new drug-delivery systems in the future.

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Year:  2001        PMID: 11470609     DOI: 10.1016/s1367-5931(00)00227-1

Source DB:  PubMed          Journal:  Curr Opin Chem Biol        ISSN: 1367-5931            Impact factor:   8.822


  66 in total

1.  Controlled release pulmonary administration of curcumin using swellable biocompatible microparticles.

Authors:  Ibrahim M El-Sherbiny; Hugh D C Smyth
Journal:  Mol Pharm       Date:  2011-12-28       Impact factor: 4.939

2.  Antitumor activity of peptide amphiphile nanofiber-encapsulated camptothecin.

Authors:  Stephen Soukasene; Daniel J Toft; Tyson J Moyer; Hsuming Lu; Hyung-Kun Lee; Stephany M Standley; Vincent L Cryns; Samuel I Stupp
Journal:  ACS Nano       Date:  2011-11-01       Impact factor: 15.881

Review 3.  Degradable Controlled-Release Polymers and Polymeric Nanoparticles: Mechanisms of Controlling Drug Release.

Authors:  Nazila Kamaly; Basit Yameen; Jun Wu; Omid C Farokhzad
Journal:  Chem Rev       Date:  2016-02-08       Impact factor: 60.622

4.  Enzymatic Polymerization of an Ibuprofen-Containing Monomer and Subsequent Drug Release.

Authors:  Nicholas D Stebbins; Weiling Yu; Kathryn E Uhrich
Journal:  Macromol Biosci       Date:  2015-04-16       Impact factor: 4.979

Review 5.  Drug release kinetics and transport mechanisms of non-degradable and degradable polymeric delivery systems.

Authors:  Yao Fu; Weiyuan John Kao
Journal:  Expert Opin Drug Deliv       Date:  2010-04       Impact factor: 6.648

6.  Solid-phase synthesis and kinetic characterization of fluorogenic enzyme-degradable hydrogel cross-linkers.

Authors:  Jason A Moss; Shula Stokols; Mark S Hixon; Fawn T Ashley; Jason Y Chang; Kim D Janda
Journal:  Biomacromolecules       Date:  2006-04       Impact factor: 6.988

Review 7.  Particle shape: a new design parameter for micro- and nanoscale drug delivery carriers.

Authors:  Julie A Champion; Yogesh K Katare; Samir Mitragotri
Journal:  J Control Release       Date:  2007-04-11       Impact factor: 9.776

Review 8.  Nanoparticulate systems for growth factor delivery.

Authors:  Sufeng Zhang; Hasan Uludağ
Journal:  Pharm Res       Date:  2009-05-05       Impact factor: 4.200

9.  Biodegradable polyesters containing ibuprofen and naproxen as pendant groups.

Authors:  Roselin Rosario-Meléndez; Weiling Yu; Kathryn E Uhrich
Journal:  Biomacromolecules       Date:  2013-09-06       Impact factor: 6.988

10.  Intraperitoneal delivery of paclitaxel by poly(ether-anhydride) microspheres effectively suppresses tumor growth in a murine metastatic ovarian cancer model.

Authors:  Ming Yang; Tao Yu; Joseph Wood; Ying-Ying Wang; Benjamin C Tang; Qi Zeng; Brian W Simons; Jie Fu; Chi-Mu Chuang; Samuel K Lai; T-C Wu; Chien-Fu Hung; Justin Hanes
Journal:  Drug Deliv Transl Res       Date:  2014-04-01       Impact factor: 4.617

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