| Literature DB >> 11468320 |
O Diav-Citrin1, S Shechtman, J Arnon, A Ornoy.
Abstract
The Israeli Teratogen Information Service prospectively followed up 210 pregnancies with first trimester carbamazepine exposure. Pregnancy outcome was compared with that of two overlapping controls, matched and general (n = 629), exposed to nonteratogenic agents. Our study suggests a twofold increase in the rate of major congenital anomalies (12/160 [carbamazepine] versus 18/560 [general control]; relative risk 2.24; 95% CI 1.1-4.56) and a birth weight reduction of approximately 250 g after in utero exposure to carbamazepine.Entities:
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Year: 2001 PMID： 11468320 DOI： 10.1212/wnl.57.2.321
Source DB: PubMed Journal: Neurology ISSN： 0028-3878 Impact factor: 9.910