Literature DB >> 11467746

Structural features of trinucleotide repeats associated with DNA expansion.

I V Kovtun1, G Goellner, C T McMurray.   

Abstract

The mechanism of DNA expansion is not well understood. Recent evidence from genetic, in vivo, and in vitro studies has suggested a link between the formation of alternative DNA secondary structures by trinucleotide repeat tracts and their propensity to undergo expansion. This review will focus on structural features and the mechanism of expansion relevant to human disease.

Entities:  

Mesh：

Substances：

Year:  2001        PMID： 11467746

Source DB:  PubMed          Journal:  Biochem Cell Biol        ISSN： 0829-8211            Impact factor:   3.626


  21 in total

1.  Complementary roles for exonuclease 1 and Flap endonuclease 1 in maintenance of triplet repeats.

Authors:  Aarthy C Vallur; Nancy Maizels
Journal:  J Biol Chem       Date:  2010-07-19       Impact factor: 5.157

2.  Mutsβ generates both expansions and contractions in a mouse model of the Fragile X-associated disorders.

Authors:  Xiao-Nan Zhao; Daman Kumari; Shikha Gupta; Di Wu; Maya Evanitsky; Wei Yang; Karen Usdin
Journal:  Hum Mol Genet       Date:  2015-09-29       Impact factor: 6.150

3.  OGG1 initiates age-dependent CAG trinucleotide expansion in somatic cells.

Authors:  Irina V Kovtun; Yuan Liu; Magnar Bjoras; Arne Klungland; Samuel H Wilson; Cynthia T McMurray
Journal:  Nature       Date:  2007-04-22       Impact factor: 49.962

4.  DNA energy landscapes via calorimetric detection of microstate ensembles of metastable macrostates and triplet repeat diseases.

Authors:  Jens Völker; Horst H Klump; Kenneth J Breslauer
Journal:  Proc Natl Acad Sci U S A       Date:  2008-11-17       Impact factor: 11.205

Review 5.  Mutational dynamics of microsatellites.

Authors:  Atul Bhargava; F F Fuentes
Journal:  Mol Biotechnol       Date:  2010-03       Impact factor: 2.695

Review 6.  DNA triplet repeat expansion and mismatch repair.

Authors:  Ravi R Iyer; Anna Pluciennik; Marek Napierala; Robert D Wells
Journal:  Annu Rev Biochem       Date:  2015-01-02       Impact factor: 23.643

7.  Amino acid runs in eukaryotic proteomes and disease associations.

Authors:  Samuel Karlin; Luciano Brocchieri; Aviv Bergman; Jan Mrazek; Andrew J Gentles
Journal:  Proc Natl Acad Sci U S A       Date:  2002-01-08       Impact factor: 11.205

8.  Saccharomyces cerevisiae Srs2 DNA helicase selectively blocks expansions of trinucleotide repeats.

Authors:  Saumitri Bhattacharyya; Robert S Lahue
Journal:  Mol Cell Biol       Date:  2004-09       Impact factor: 4.272

9.  Mutations in yeast replication proteins that increase CAG/CTG expansions also increase repeat fragility.

Authors:  Julie L Callahan; Kenneth J Andrews; Virginia A Zakian; Catherine H Freudenreich
Journal:  Mol Cell Biol       Date:  2003-11       Impact factor: 4.272

10.  Identification of the Schistosoma mansoni TNF-alpha receptor gene and the effect of human TNF-alpha on the parasite gene expression profile.

Authors:  Katia C Oliveira; Mariana L P Carvalho; Thiago M Venancio; Patricia A Miyasato; Toshie Kawano; Ricardo DeMarco; Sergio Verjovski-Almeida
Journal:  PLoS Negl Trop Dis       Date:  2009-12-01
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.