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Literature DB >> 11466296

YLR209c encodes Saccharomyces cerevisiae purine nucleoside phosphorylase.

K Lecoq¹, I Belloc, C Desgranges, M Konrad, B Daignan-Fornier.

Abstract

The yeast YLR209c (PNP1) gene encodes a protein highly similar to purine nucleoside phosphorylases. This protein specifically metabolized inosine and guanosine. Disruption of PNP1 led to inosine and guanosine excretion in the medium, thus showing that PNP1 plays an important role in the metabolism of these purine nucleosides in vivo.

Entities: Chemical Gene Species

Mesh：

Substances：

Year: 2001 PMID： 11466296 PMCID： PMC99547 DOI： 10.1128/JB.183.16.4910-4913.2001

Source DB: PubMed Journal: J Bacteriol ISSN： 0021-9193 Impact factor: 3.490

19 in total

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4. Isolation and characterization of the Saccharomyces cerevisiae XPT1 gene encoding xanthine phosphoribosyl transferase.

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Authors: G Koellner; M Luić; D Shugar; W Saenger; A Bzowska
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8. Human purine nucleoside phosphorylase cDNA sequence and genomic clone characterization.

Authors: S R Williams; J M Goddard; D W Martin
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10. Purification and some properties of an IMP-specific 5'-nucleotidase from yeast.

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6. Nicotinamide riboside and nicotinic acid riboside salvage in fungi and mammals. Quantitative basis for Urh1 and purine nucleoside phosphorylase function in NAD+ metabolism.

Authors: Peter Belenky; Kathryn C Christensen; Francesca Gazzaniga; Alexandre A Pletnev; Charles Brenner
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7. Functional and Structural Characterization of Purine Nucleoside Phosphorylase from Kluyveromyces lactis and Its Potential Applications in Reducing Purine Content in Food.

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