| Literature DB >> 11463987 |
M A Smith1, C J Pallister, J G Smith.
Abstract
The type III tyrosine kinase receptor c-KIT and its ligand stem cell factor (SCF; also known as KIT ligand, mast cell growth factor and steel factor) are closely involved in the regulation of a wide range of tissues at different stages of life. This review provides an outline of the discovery, structure and expression of SCF and c-KIT but concentrates on their respective roles in the regulation of human haemopoiesis and how this knowledge might be exploited in the clinical setting. Copyright 2001 S. Karger AG, BaselEntities:
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Year: 2001 PMID： 11463987 DOI： 10.1159/000046556
Source DB: PubMed Journal: Acta Haematol ISSN： 0001-5792 Impact factor: 2.195