| Literature DB >> 11463298 |
D Takano1, T Nagamitsu, H Ui, K Shiomi, Y Yamaguchi, R Masuma, I Kuwajima, S Omura.
Abstract
[structure: see text] Total synthesis of nafuredin, a selective NADH-fumarate reductase inhibitor, has been accomplished by a convergent approach. The C1-C8 and C9-C18 segments were derived efficiently from D-glucose and (S)-(-)-2-methyl-1-butanol, respectively, coupled by stereoselective Julia olefination, and converted to nafuredin.Entities:
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Year: 2001 PMID： 11463298 DOI： 10.1021/ol010089t
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005