OBJECTIVE: to determine whether serum elastin-derived peptides (S-EDP), are lower in patients with ruptured abdominal aortic aneurysms (rAAA) than asymptomatic (aAAA). MATERIALS AND METHODS: serum samples were collected preoperatively from 45 consecutive patients with aAAA and 15 haemodynamically stable patients with rAAA. S-EDP (ng/ml) was measured by a competitive enzyme-linked immunosorbent assay (ELISA). RESULTS: S-EDP (mean +/- s.d.) was significantly lower in patients with rAAA (31.6 ng/ml +/- 6.8) than in patients with aAAA (39.4 ng/ml +/- 8.0 p=0.001). CONCLUSION: patients with rAAA had significantly lower levels of S-EDP than patients with aAAA. The possibility that S-EDP can be used to identify patients at increased risk of rupture requires further investigation. Copyright 2001 Harcourt Publishers Limited.
OBJECTIVE: to determine whether serum elastin-derived peptides (S-EDP), are lower in patients with ruptured abdominal aortic aneurysms (rAAA) than asymptomatic (aAAA). MATERIALS AND METHODS: serum samples were collected preoperatively from 45 consecutive patients with aAAA and 15 haemodynamically stable patients with rAAA. S-EDP (ng/ml) was measured by a competitive enzyme-linked immunosorbent assay (ELISA). RESULTS:S-EDP (mean +/- s.d.) was significantly lower in patients with rAAA (31.6 ng/ml +/- 6.8) than in patients with aAAA (39.4 ng/ml +/- 8.0 p=0.001). CONCLUSION:patients with rAAA had significantly lower levels of S-EDP than patients with aAAA. The possibility that S-EDP can be used to identify patients at increased risk of rupture requires further investigation. Copyright 2001 Harcourt Publishers Limited.
Authors: M J Nielsen; J Lehmann; D J Leeming; R Schierwagen; S Klein; C Jansen; C P Strassburg; F Bendtsen; S Møller; T Sauerbruch; M A Karsdal; A Krag; J Trebicka Journal: Dig Dis Sci Date: 2015-07-03 Impact factor: 3.199
Authors: Helene Skjøt-Arkil; Rikke E Clausen; Lars M Rasmussen; Wanchun Wang; Yaguo Wang; Qinlong Zheng; Hans Mickley; Lotte Saaby; Axel C P Diederichsen; Jess Lambrechtsen; Fernando J Martinez; Cory M Hogaboam; Meilan Han; Martin R Larsen; Arkadiusz Nawrocki; Ben Vainer; Dorrit Krustrup; Marina Bjørling-Poulsen; Morten A Karsdal; Diana J Leeming Journal: PLoS One Date: 2013-06-21 Impact factor: 3.240
Authors: Helene Skjøt-Arkil; Rikke E Clausen; Quoc Hai Trieu Nguyen; Yaguo Wang; Qinlong Zheng; Fernando J Martinez; Cory M Hogaboam; Meilan Han; Lloyd B Klickstein; Martin R Larsen; Arkadiusz Nawrocki; Diana J Leeming; Morten A Karsdal Journal: BMC Pulm Med Date: 2012-07-20 Impact factor: 3.317
Authors: Görkem Yiğit; Ferit Çetinkaya; Bahadır Aytekin; Mehmet Ali Türkçü; Anıl Özen; Ahmet Sarıtaş Journal: Kardiochir Torakochirurgia Pol Date: 2019-10-28
Authors: Ify R Mordi; Rachael O Forsythe; Corry Gellatly; Zaid Iskandar; Olivia M McBride; Athanasios Saratzis; Rod Chalmers; Calvin Chin; Matthew J Bown; David E Newby; Chim C Lang; Jeffrey T J Huang; Anna-Maria Choy Journal: J Am Heart Assoc Date: 2019-10-09 Impact factor: 5.501
Authors: Menno E Groeneveld; Jorn P Meekel; Sidney M Rubinstein; Lisanne R Merkestein; Geert Jan Tangelder; Willem Wisselink; Maarten Truijers; Kak Khee Yeung Journal: J Am Heart Assoc Date: 2018-06-30 Impact factor: 5.501