Literature DB >> 11460549

Nuclear magnetic resonance-based approaches for lead generation in drug discovery.

J W Peng1, C A Lepre, J Fejzo, N Abdul-Manan, J M Moore.   

Abstract

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Year:  2001        PMID： 11460549     DOI： 10.1016/s0076-6879(02)38221-1

Source DB:  PubMed          Journal:  Methods Enzymol        ISSN： 0076-6879            Impact factor:   1.600


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  15 in total

1.  Rational design, synthesis, and verification of affinity ligands to a protein surface cleft.

Authors:  Herbert Baumann; Sara Ohrman; Yasuro Shinohara; Oguz Ersoy; Devapriya Choudhury; Andreas Axén; Ulf Tedebark; Enrique Carredano
Journal:  Protein Sci       Date:  2003-04       Impact factor: 6.725

2.  Determining the optimal size of small molecule mixtures for high throughput NMR screening.

Authors:  Kelly A Mercier; Robert Powers
Journal:  J Biomol NMR       Date:  2005-03       Impact factor: 2.835

Review 3.  Application of NMR and molecular docking in structure-based drug discovery.

Authors:  Jaime L Stark; Robert Powers
Journal:  Top Curr Chem       Date:  2012

4.  The STINT-NMR method for studying in-cell protein-protein interactions.

Authors:  David S Burz; Alexander Shekhtman
Journal:  Curr Protoc Protein Sci       Date:  2010-08

5.  Binding site identification and structure determination of protein-ligand complexes by NMR a semiautomated approach.

Authors:  Joshua J Ziarek; Francis C Peterson; Betsy L Lytle; Brian F Volkman
Journal:  Methods Enzymol       Date:  2011       Impact factor: 1.600

6.  Discovery of Novel Allosteric Eg5 Inhibitors Through Structure-Based Virtual Screening.

Authors:  Wei Zhang; Ling Zhai; Wenyan Lu; Rebecca J Boohaker; Indira Padmalayam; Yonghe Li
Journal:  Chem Biol Drug Des       Date:  2016-03-06       Impact factor: 2.817

Review 7.  High-field solution NMR spectroscopy as a tool for assessing protein interactions with small molecule ligands.

Authors:  Andria L Skinner; Jennifer S Laurence
Journal:  J Pharm Sci       Date:  2008-11       Impact factor: 3.534

8.  Screening of small molecule interactor library by using in-cell NMR spectroscopy (SMILI-NMR).

Authors:  Jingjing Xie; Rajiv Thapa; Sergey Reverdatto; David S Burz; Alexander Shekhtman
Journal:  J Med Chem       Date:  2009-06-11       Impact factor: 7.446

9.  A novel and conserved pocket of human kappa-Fab fragments: design, synthesis, and verification of directed affinity ligands.

Authors:  Enrique Carredano; Herbert Baumann; Anna Grönberg; Nils Norrman; Gunnar Glad; Jinyu Zou; Oguz Ersoy; Elles Steensma; Andreas Axén
Journal:  Protein Sci       Date:  2004-06       Impact factor: 6.725

10.  A novel method of production and biophysical characterization of the catalytic domain of yeast oligosaccharyl transferase.

Authors:  Chengdong Huang; Smita Mohanty; Monimoy Banerjee
Journal:  Biochemistry       Date:  2010-02-16       Impact factor: 3.162
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