Regulatory issues in pain management.

Patients commonly are left to suffer from pain that affects their daily lives. The prevalence of undertreated, moderate to severe pain is a public health problem in many countries, including the United States. In many cases, opioids should be the mainstay for the treatment of this level of pain, but they often are not used or are underdosed. One of the reasons for this underuse most cited by health care professionals is their fear of sanctions by their governing boards, law enforcement, or their misunderstanding of the laws and regulations governing the use of these controlled substances. This article reviews some of the relevant issues of the regulation of controlled substances, updates the reader about the laws, and provides guidance to practitioners about the appropriate use of controlled substances, especially opioids, to manage pain.