OBJECTIVE: To find the prevalence of orthostatic hypotension (OH) and associated factors in elderly hypertensive patients in a primary care setting. DESIGN: Descriptive cross-sectional study. SETTING: La Marina Health Centre (an urban centre in Santander). PATIENTS: A random sample of 295 patients aged 65 years or older regularly assisted from hypertension. MEASUREMENTS AND MAIN RESULTS: Measurements of sitting and standing blood pressure were obtained. Orthostatic hypotension was defined as 20 mmHg or greater decrease in systolic or 10 mmHg or greater decrease in diastolic blood pressure after 1-minute or 5-minute standing. Associated diseases, symptoms upon standing, medication use, habits and other clinical assessments were also recorded. The prevalence of OH was 14.6%. The prevalence of systolic OH after 1-minute (OH-S1) and after 5-minute (OH-S5) standing was 5.8% in both, and the diastolic OH was 5.1% after 1-minute (OH-D1) and 4.1% after 5-minute (OH-D5) standing. By logistic regression analysis, association between higher level of systolic blood pressure and global OH was found, also with the presence of orthostatic intolerance symptoms (although only 25.6% of the patients with OH showed symptoms) and smoking. Beta-blockers and calcium channel blockers (different from dihydropyridines) use was associated with OH after 1-minute standing and smoking with OH after 5-minute standing. CONCLUSIONS: The detected prevalence is high and justifies the case finding of OH in elderly hypertensive patients in primary care. The symptoms of orthostatic intolerance are correlated with OH, but only 1 out of 4 patients showed symptoms. Smoking could be related with OH, so beta-blockers and calcium channel blockers (different from dihydropyridines) use.
OBJECTIVE: To find the prevalence of orthostatic hypotension (OH) and associated factors in elderly hypertensivepatients in a primary care setting. DESIGN: Descriptive cross-sectional study. SETTING: La Marina Health Centre (an urban centre in Santander). PATIENTS: A random sample of 295 patients aged 65 years or older regularly assisted from hypertension. MEASUREMENTS AND MAIN RESULTS: Measurements of sitting and standing blood pressure were obtained. Orthostatic hypotension was defined as 20 mmHg or greater decrease in systolic or 10 mmHg or greater decrease in diastolic blood pressure after 1-minute or 5-minute standing. Associated diseases, symptoms upon standing, medication use, habits and other clinical assessments were also recorded. The prevalence of OH was 14.6%. The prevalence of systolic OH after 1-minute (OH-S1) and after 5-minute (OH-S5) standing was 5.8% in both, and the diastolic OH was 5.1% after 1-minute (OH-D1) and 4.1% after 5-minute (OH-D5) standing. By logistic regression analysis, association between higher level of systolic blood pressure and global OH was found, also with the presence of orthostatic intolerance symptoms (although only 25.6% of the patients with OH showed symptoms) and smoking. Beta-blockers and calcium channel blockers (different from dihydropyridines) use was associated with OH after 1-minute standing and smoking with OH after 5-minute standing. CONCLUSIONS: The detected prevalence is high and justifies the case finding of OH in elderly hypertensivepatients in primary care. The symptoms of orthostatic intolerance are correlated with OH, but only 1 out of 4 patients showed symptoms. Smoking could be related with OH, so beta-blockers and calcium channel blockers (different from dihydropyridines) use.
Authors: C Di Stefano; V Milazzo; S Totaro; G Sobrero; A Ravera; A Milan; S Maule; F Veglio Journal: J Hum Hypertens Date: 2015-01-29 Impact factor: 3.012
Authors: Christopher Elles Clark; Daniel Thomas; Fiona C Warren; David J Llewellyn; Luigi Ferrucci; John L Campbell Journal: BMJ Open Date: 2018-04-20 Impact factor: 2.692
Authors: Francisco Javier Formigo Couceiro; Marta Pena Seijo; Antonio Pose Reino; José Manuel Mayán Santos; Francisco Javier Ayape Amigot; Jesús Sueiro Justel Journal: Aten Primaria Date: 2018-03-30 Impact factor: 1.137