Literature DB >> 11458645

[Pharmacologic analysis of the radiation-protecting effect of indraline].

M V Vasin1, I B Ushakov, L A Semenova, V Iu Kovtun.   

Abstract

In comparative studies of the influence of selective alpha 1-adrenoblockager prazosine on radioprotective effect of indraline and mesotone it was found that the mechanism for their radioprotective effect was completely realized via alpha 1-adrenergic action. Calcium blockager nifedipine did not block the indraline effect. It was discussed the issue of classifying of indraline as alpha 1B-adrenomimetic.

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Year:  2001        PMID： 11458645

Source DB:  PubMed          Journal:  Radiats Biol Radioecol        ISSN： 0869-8031


  3 in total

Review 1.  Comparative efficacy and the window of radioprotection for adrenergic and serotoninergic agents and aminothiols in experiments with small and large animals.

Authors:  Mikhail V Vasin; Igor B Ushakov
Journal:  J Radiat Res       Date:  2014-10-13       Impact factor: 2.724

Review 2.  Comments on the mechanisms of action of radiation protective agents: basis components and their polyvalence.

Authors:  Mikhail V Vasin
Journal:  Springerplus       Date:  2014-08-07

3.  Protective effect and the therapeutic index of indralin in juvenile rhesus monkeys.

Authors:  Mikhail V Vasin; Leonid F Semenov; Nikolai N Suvorov; Vsevolod V Antipov; Igor B Ushakov; Leonid A Ilyin; Boris A Lapin
Journal:  J Radiat Res       Date:  2014-07-10       Impact factor: 2.724
  3 in total

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