Literature DB >> 11458461

1-O-galloyl-6-O-(4-hydroxy-3,5-dimethoxy)benzoyl-beta-D-glucose, a new hepatoprotective constituent from Combretum quadrangulare.

I K Adnyana, Y Tezuka, S Awale, A H Banskota, K Q Tran, S Kadota.   

Abstract

A new gallic acid derivative, 1-O-galloyl-6-O-(4-hydroxy-3,5-dimethoxy)benzoyl-beta-D-glucose (1) has been isolated from an H2O-fraction of MeOH extract of Combretum quadrangulare seeds. Compound 1 exhibited potent hepatoprotective activity against D-GalN/TNF-alpha-induced cell death in primary cultured mouse hepatocytes with an IC50 of 3.3 microM.

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Year:  2001        PMID: 11458461     DOI: 10.1055/s-2001-14318

Source DB:  PubMed          Journal:  Planta Med        ISSN: 0032-0943            Impact factor:   3.352


  3 in total

Review 1.  Bioactivities of the genus Combretum (Combretaceae): a review.

Authors:  Gedson Rodrigues de Morais Lima; Igor Rafael Praxedes de Sales; Marcelo Ricardo Dutra Caldas Filho; Neyres Zínia Taveira de Jesus; Heloina de Sousa Falcão; José Maria Barbosa-Filho; Analúcia Guedes Silveira Cabral; Augusto Lopes Souto; Josean Fechine Tavares; Leônia Maria Batista
Journal:  Molecules       Date:  2012-08-02       Impact factor: 4.411

2.  Phytochemical Profile, Antioxidant Activity, and Cytotoxicity Assessment of Tagetes erecta L. Flowers.

Authors:  Ana Flavia Burlec; Łukasz Pecio; Solomiia Kozachok; Cornelia Mircea; Andreia Corciovă; Liliana Vereștiuc; Oana Cioancă; Wiesław Oleszek; Monica Hăncianu
Journal:  Molecules       Date:  2021-02-24       Impact factor: 4.411

3.  Bioactive pentacyclic triterpenes from the stems of Combretum laxum.

Authors:  Eder Bisoli; Walmir Silva Garcez; Lidilhone Hamerski; Caroline Tieppo; Fernanda Rodrigues Garcez
Journal:  Molecules       Date:  2008-11-01       Impact factor: 4.411

  3 in total

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