| Literature DB >> 11457515 |
S Tanganelli1, K Fuxe, T Antonelli, W T O'Connor, L Ferraro.
Abstract
The present article reviews our recent biochemical and microdialysis studies showing the evidence for an antagonistic CCK(B)/D(2) receptor interaction in the regulation of dopaminergic transmission in the nucleus accumbens and GABAergic transmission in the ipsilateral ventral pallidum. Since the nucleus accumbens plays a crucial role in regulating the output from the limbic system and consequently motivation, it may be speculated that a dysregulation of this receptor interaction may have consequences in a wide range of central nervous system disorders.Entities:
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Year: 2001 PMID: 11457515 DOI: 10.1016/s0196-9781(01)00446-6
Source DB: PubMed Journal: Peptides ISSN: 0196-9781 Impact factor: 3.750