Literature DB >> 11456647

Highly diastereoselective and enantioselective carbon-carbon bond formations in conjugate additions of lithiated N-Boc allylamines to nitroalkenes: enantioselective synthesis of 3,4- and 3,4,5-substituted piperidines including (-)-paroxetine.

T A Johnson1, M D Curtis, P Beak.   

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Year:  2001        PMID: 11456647     DOI: 10.1021/ja005748w

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN: 0002-7863            Impact factor:   15.419


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  2 in total

1.  Chemical and structural investigation of the paroxetine-human serotonin transporter complex.

Authors:  Jonathan A Coleman; Vikas Navratna; Daniele Antermite; Dongxue Yang; James A Bull; Eric Gouaux
Journal:  Elife       Date:  2020-07-03       Impact factor: 8.140

2.  Rapid Construction of (-)-Paroxetine and (-)-Femoxetine via N-Heterocyclic Carbene Catalyzed Homoenolate Addition to Nitroalkenes.

Authors:  Nicholas A White; Kerem E Ozboya; Darrin M Flanigan; Tomislav Rovis
Journal:  Asian J Org Chem       Date:  2014-04       Impact factor: 3.319

  2 in total

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