Literature DB >> 11454470

Substituted 4-phenyl-2-(phenylcarboxamido)-1,3-thiazole derivatives as antagonists for the adenosine A(1) receptor.

E W van Tilburg1, P A van der Klein, M de Groote, M W Beukers, A P IJzerman.   

Abstract

The synthesis and receptor binding of novel adenosine receptor antagonists is described. We found that non-xanthine 4-phenyl-2-(phenylcarboxamido)-1,3-thiazole derivatives may have high affinity and substantial selectivity for the adenosine A(1) receptor.

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Year:  2001        PMID： 11454470     DOI： 10.1016/s0960-894x(01)00356-0

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  3 in total

1.  Functional selectivity of adenosine A1 receptor ligands?

Authors:  Ellen V Langemeijer; Dennis Verzijl; Stefan J Dekker; Ad P Ijzerman
Journal:  Purinergic Signal       Date:  2012-09-28       Impact factor: 3.765

Review 2.  Progress in the pursuit of therapeutic adenosine receptor antagonists.

Authors:  Stefano Moro; Zhan-Guo Gao; Kenneth A Jacobson; Giampiero Spalluto
Journal:  Med Res Rev       Date:  2006-03       Impact factor: 12.388

3.  Synthesis of novel thiazole, pyranothiazole, thiazolo[4,5-b]pyridines and thiazolo[5',4':5,6]pyrano[2,3-d]pyrimidine derivatives and incorporating isoindoline-1,3-dione group.

Authors:  Mona A Hosny; Yasser H Zaki; Wafaa A Mokbel; Abdou O Abdelhamid
Journal:  BMC Chem       Date:  2019-03-26
  3 in total

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