Literature DB >> 1145417

Experimental cerebral vasospasm in cats: modification by a new synthetic vasodilator YC-93.

Y Handa, S Yoneda, T Koyama, M Matsuda, H Handa.   

Abstract

Effects of a new synthetic vasodilator, YC-93, a derivative of 1. 4-dihydropyridine, on experimental cerebral vasospasm, were studies in cats. A topical administration of YC-93 solution was found to rapidly reverse the spasm of the basilar artery induced with a subarachnoi application of fresh blood, serotonin or porstaglandin F2 alpha. Pretreatment of the basilar artery with YC-93 prevented the development of experimental vasospasm with all these agents.

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Year:  1975        PMID： 1145417

Source DB:  PubMed          Journal:  Surg Neurol        ISSN： 0090-3019


  10 in total

1.  Experimental cerebral vasospasm: resolution by iloprost.

Authors:  N Egemen; K Birler; N Avman; R K Türker
Journal:  Acta Neurochir (Wien)       Date:  1988       Impact factor: 2.216

2.  Experimental basilar artery spasm caused by autologous blood application: effects of clot removal and topical nicardipine.

Authors:  R Tuncer
Journal:  Acta Neurochir (Wien)       Date:  1993       Impact factor: 2.216

3.  The effect of acute and chronic nicardipine therapy on forearm arterial haemodynamics in essential hypertension.

Authors:  J Levenson; A C Simon; J Bouthier; B C Maarek; M E Safar
Journal:  Br J Clin Pharmacol       Date:  1985       Impact factor: 4.335

4.  Intracranial effects of nicardipine.

Authors:  M R Gaab; T Czech; A Korn
Journal:  Br J Clin Pharmacol       Date:  1985       Impact factor: 4.335

Review 5.  'Second generation' dihydropyridine calcium antagonists. Greater vascular selectivity and some unique applications.

Authors:  D D Freedman; D D Waters
Journal:  Drugs       Date:  1987-11       Impact factor: 9.546

6.  Nicardipine HCl: clinical experience in patients undergoing anaesthesia for intracranial aneurysm clipping.

Authors:  D S Warner; M D Sokoll; M Maktabi; J C Godersky; H P Adams
Journal:  Can J Anaesth       Date:  1989-03       Impact factor: 5.063

7.  Effects of prophylactic intrathecal administrations of nicardipine on vasospasm in patients with severe aneurysmal subarachnoid haemorrhage.

Authors:  M Shibuya; Y Suzuki; H Enomoto; T Okada; K Ogura; K Sugita
Journal:  Acta Neurochir (Wien)       Date:  1994       Impact factor: 2.216

8.  Effects of nicardipine treatment on Na(+)-K+ ATPase and lipid peroxidation after experimental subarachnoid haemorrhage.

Authors:  F Marzatico; P Gaetani; G Spanu; E Buratti; R Rodriguez y Baena
Journal:  Acta Neurochir (Wien)       Date:  1991       Impact factor: 2.216

Review 9.  Nicardipine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy, in the treatment of angina pectoris, hypertension and related cardiovascular disorders.

Authors:  E M Sorkin; S P Clissold
Journal:  Drugs       Date:  1987-04       Impact factor: 9.546

10.  Cardiovascular pharmacology of nicardipine in animals.

Authors:  T Takenaka; M Asano; K Shiono; M Shibasaki; O Inagaki
Journal:  Br J Clin Pharmacol       Date:  1985       Impact factor: 4.335
  10 in total

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