Literature DB >> 11452981

New quinone-amino acid conjugates linked via a vinylic spacer.

M Alnabari1, S Bittner.   

Abstract

Chloranil and 2,3-dichloro-1,4-naphthoquinone have been linked to different natural and unnatural amino acids via a vinylic spacer. Two routes were developed for the facile preparation of these novel modified amino acids: the direct method, which can only be applied to secondary amines, and the indirect method (transamination reaction), which can be applied to any amino acid or ester.

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Year:  2001        PMID: 11452981     DOI: 10.1007/s007260170034

Source DB:  PubMed          Journal:  Amino Acids        ISSN: 0939-4451            Impact factor:   3.520


  2 in total

1.  One-pot chemical synthesis of small ubiquitin-like modifier protein-peptide conjugates using bis(2-sulfanylethyl)amido peptide latent thioester surrogates.

Authors:  Emmanuelle Boll; Hervé Drobecq; Nathalie Ollivier; Annick Blanpain; Laurent Raibaut; Rémi Desmet; Jérôme Vicogne; Oleg Melnyk
Journal:  Nat Protoc       Date:  2015-01-15       Impact factor: 13.491

2.  Access to New Cytotoxic Quinone-Amino Acid Conjugates Linked through A Vinylic Spacer from 2-Acylnaphthoquinones and Methyl 3-Aminocrotonate.

Authors:  Jaime A Valderrama; Joel Garrido; Virginia Delgado; Julio Benites; Cristina Theoduloz
Journal:  Molecules       Date:  2017-12-20       Impact factor: 4.411

  2 in total

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