Literature DB >> 11452385

Isolation and characterization of human foetal alpha-globulin (alpha 1F) from foetal and hepatoma sera.

A Adinolfi1, M Adinolfi, S Cohen.   

Abstract

The alpha 1F present in human foetal sera and the serum from a patient with hepatocellular carcinoma was isolated by immune precipitation using rabbit anti-alpha 1F. After labelling with 125I, some physicochemical properties of alpha 1F were investigated. The molecular weights of 125I-labelled alpha 1F isolated from foetal and hepatoma sera were 61,000 and 63,000, respectively. The protein was not dissociated in 6 M guanidine after complete reduction, showing that it contains a single peptide chain.

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Year:  1971        PMID: 11452385     DOI: 10.1016/0005-2795(71)90103-6

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN: 0006-3002


  4 in total

Review 1.  [Carcinofetal antigens. I. alpha-fetoprotein (author's transl)].

Authors:  R Lamerz; A Fateh-Moghadam
Journal:  Klin Wochenschr       Date:  1975-02-15

2.  [Alpha-fetoprotein and cystic fibrosis (author's transl)].

Authors:  T Lücking; P Mariss
Journal:  Klin Wochenschr       Date:  1976-04-15

3.  Alpha-feto-protein during development and in disease.

Authors:  A Adinolfi; M Adinolfi
Journal:  J Med Genet       Date:  1975-06       Impact factor: 6.318

4.  Demonstration of the inhibitory effect of human alpha-fetoprotein on in vitro transformation of human lymphocytes.

Authors:  S Yachnin
Journal:  Proc Natl Acad Sci U S A       Date:  1976-08       Impact factor: 11.205

  4 in total

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