Literature DB >> 1145201

Dichloroacetamide antidotes for thiocarbamate herbicides: mode of action.

M Lay, J P Hubbell, J E Casida.   

Abstract

Thiocarbamate sulfoxides formed on metabolic sulfoxidation of thicoarbamate herbicides in plants and mammals are effective carbamoylating agents for glutathione and other tissue thiols. Dichloracetamides that protect corn from thiocarbamate herbicide injury more rapid detoxification of the thiocarbamate sulfoxides by increasing their rate of carbamoylation of glutathione through elevation of the root glutathione level and glutathione s-transferase activity.

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Year:  1975        PMID： 1145201     DOI： 10.1126/science.1145201

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  5 in total

Review 1.  Detoxification without intoxication: herbicide safeners activate plant defense gene expression.

Authors:  Dean E Riechers; Klaus Kreuz; Qin Zhang
Journal:  Plant Physiol       Date:  2010-03-17       Impact factor: 8.340

2.  Different rates of metabolism of two chloroacetanilide herbicides in pioneer 3320 corn.

Authors:  K M O'connell; E J Breaux; R T Fraley
Journal:  Plant Physiol       Date:  1988-02       Impact factor: 8.340

3.  Herbicide safener-binding protein of maize. Purification, cloning, and expression of an encoding cDNA.

Authors:  J S Scott-Craig; J E Casida; L Poduje; J D Walton
Journal:  Plant Physiol       Date:  1998-03       Impact factor: 8.340

4.  The greening of pesticide-environment interactions: some personal observations.

Authors:  John E Casida
Journal:  Environ Health Perspect       Date:  2012-01-18       Impact factor: 9.031

Review 5.  Comparative aspects of pesticide metabolism in plants and animals.

Authors:  J J Menn
Journal:  Environ Health Perspect       Date:  1978-12       Impact factor: 9.031
  5 in total

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