| Literature DB >> 11451704 |
M Kretschmar1, G Geginat, T Bertsch, S Walter, H Hof, T Nichterlein.
Abstract
Liposomal amphotericin B was immunosuppressive on target cell lysis in vitro and on protection mediated by cytotoxic CD8 T cells in murine listeriosis. When dosages usually used for therapy in humans were compared, the immunosuppressive effect of 5 mg of liposomal amphotericin B/kg of body weight/day was similar to that of standard amphotericin B at 1 mg/kg/day, but a dosage of liposomal amphotericin B of 1 mg/kg/day was not suppressive in vivo.Entities:
Mesh:
Substances:
Year: 2001 PMID: 11451704 PMCID: PMC90661 DOI: 10.1128/AAC.45.8.2383-2385.2001
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191