Literature DB >> 11451079

GHB and driving impairment.

F J Couper1, B K Logan.   

Abstract

Gamma hydroxybutyrate (GHB) was identified in the blood of 13 subjects arrested for impaired driving. GHB concentrations ranged from 26 to 155 mg/L (mean 87 mg/L, median 95 mg/L). In eight cases, GHB was the only drug detected, and signs of impairment were consistent with those of a CNS depressant, including erratic driving (weaving, swerving, ignoring road signs), confusion, incoherent speech, unresponsiveness, lack of balance, unsteady coordination, poor performances on field sobriety tests, and varying states of wakefulness. Given the ability of GHB to induce sleep and unconsciousness, it is evident from these cases that recreational use of the drug has the potential to impair a person's driving ability.

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Year:  2001        PMID: 11451079

Source DB:  PubMed          Journal:  J Forensic Sci        ISSN: 0022-1198            Impact factor:   1.832


  5 in total

1.  Effect of γ-hydroxybutyrate (GHB) on driving as measured by a driving simulator.

Authors:  Evangelia Liakoni; Delia A Dempsey; Matthew Meyers; Nancy G Murphy; Dary Fiorentino; Christopher Havel; Christine Haller; Neal L Benowitz
Journal:  Psychopharmacology (Berl)       Date:  2018-09-19       Impact factor: 4.530

2.  Blood GHB concentrations and results of medical examinations in 25 car drivers in Norway.

Authors:  Muhammad S Al-Samarraie; Ritva Karinen; Jørg Mørland; Mimi Stokke Opdal
Journal:  Eur J Clin Pharmacol       Date:  2010-08-18       Impact factor: 2.953

3.  Driving under the influence of gamma-hydroxybutyrate (GHB).

Authors:  Alan Wayne Jones; Anita Holmgren; Fredrik C Kugelberg
Journal:  Forensic Sci Med Pathol       Date:  2008-05-14       Impact factor: 2.007

Review 4.  GHB pharmacology and toxicology: acute intoxication, concentrations in blood and urine in forensic cases and treatment of the withdrawal syndrome.

Authors:  Francesco P Busardò; Alan W Jones
Journal:  Curr Neuropharmacol       Date:  2015-01       Impact factor: 7.363

Review 5.  A Brief Up-Date of the Use of Sodium Oxybate for the Treatment of Alcohol Use Disorder.

Authors:  Fabio Caputo; Teo Vignoli; Claudia Tarli; Marco Domenicali; Giorgio Zoli; Mauro Bernardi; Giovanni Addolorato
Journal:  Int J Environ Res Public Health       Date:  2016-03-05       Impact factor: 3.390

  5 in total

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