Literature DB >> 11449326

Herpes simplex virus type 2: a cause of acute retinal necrosis syndrome.

N N Markomichelakis1, P Zafirakis, P Karambogia-Karefillidi, N Drakoulis, E Vagiakou-Boudri, G Paterakis, M Apostolopoulos.   

Abstract

PURPOSE: To describe a case of herpes simplex virus type 2 (HSV-2) acute retinal necrosis syndrome (ARN) in a 13-year-old immunocompetent girl.
METHODS: Polymerase chain reaction (PCR), cultures, flow cytometry, and cytology were performed on the vitreous sample.
RESULTS: Both PCR studies and vitreous cultures revealed HSV-2 as the cause of ARN. Flow cytometry showed CD4+, CD8+, and natural killer cells. The visual outcome of the patient was 20/200.
CONCLUSION: Successful culture of HSV-2 from the vitreous specimen in a patient with ARN proved HSV-2 to be one of the causes of ARN. The successful culture of HSV-2 has not been previously reported.

Entities:  

Mesh:

Substances:

Year:  2001        PMID: 11449326     DOI: 10.1076/ocii.9.2.103.3974

Source DB:  PubMed          Journal:  Ocul Immunol Inflamm        ISSN: 0927-3948            Impact factor:   3.070


  2 in total

1.  Role of nectin-1, HVEM, and PILR-alpha in HSV-2 entry into human retinal pigment epithelial cells.

Authors:  Shripaad Y Shukla; Yogesh K Singh; Deepak Shukla
Journal:  Invest Ophthalmol Vis Sci       Date:  2009-02-21       Impact factor: 4.799

Review 2.  Acute retinal necrosis (ARN) in the context of neonatal HSV-2 exposure and subconjunctival dexamethasone: case report and literature review.

Authors:  Lindsay McGrath; Marion Woods; Lawrence Lee; Diana Conrad
Journal:  Digit J Ophthalmol       Date:  2013-05-09
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.