Literature DB >> 11448808

Treatment of post-transplant lymphoproliferative disorder with monoclonal CD20 antibody (rituximab) after heart transplantation.

N D Zilz1, L J Olson, C G McGregor.   

Abstract

Post-transplant lymphoproliferative disorder (PTLD) is a frequent and often fatal complication of organ transplantation. It most often results from an Epstein-Barr virus (EBV)-transformed B-cell clone, which expresses B-cell surface markers such as CD20. We describe a case of a heart transplant recipient who EBV seroconverted post-transplant and subsequently developed subcutaneous and lymphatic B-cell lymphoma, successfully treated with CD20 antibody (rituximab). The patient has been in remission during 10 months of clinical follow-up.

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Year:  2001        PMID: 11448808     DOI: 10.1016/s1053-2498(00)00326-0

Source DB:  PubMed          Journal:  J Heart Lung Transplant        ISSN: 1053-2498            Impact factor:   10.247


  5 in total

Review 1.  Herpesvirus infections in organ transplant recipients.

Authors:  Frank J Jenkins; David T Rowe; Charles R Rinaldo
Journal:  Clin Diagn Lab Immunol       Date:  2003-01

Review 2.  Treatment with rituximab in benign and malignant hematologic disorders in children.

Authors:  Lisa B Giulino; James B Bussel; Ellis J Neufeld
Journal:  J Pediatr       Date:  2007-04       Impact factor: 4.406

3.  Post-transplant lymphoproliferative disorder in an adolescent masquerading as a complicated primary EBV infection.

Authors:  Heather L Henry; Conrad Vincent Fernandez; Gerard Corsten
Journal:  BMJ Case Rep       Date:  2009-06-09

Review 4.  Managing post-transplant lymphoproliferative disorders in solid-organ transplant recipients: a review of immunosuppressant regimens.

Authors:  Vidhya Murukesan; Sandeep Mukherjee
Journal:  Drugs       Date:  2012-08-20       Impact factor: 9.546

5.  Management of the Patient After Heart Transplant.

Authors:  Michael A Mathier; Dennis M McNamara
Journal:  Curr Treat Options Cardiovasc Med       Date:  2004-12
  5 in total

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