Literature DB >> 11448786

Cystic fibrosis: the 'bicarbonate before chloride' hypothesis.

J J Wine1.   

Abstract

The specific effects of some mutations that cause cystic fibrosis suggest that reduced HCO(3)(-) transport is the key to understanding cystic fibrosis pathology. But there is a puzzling discrepancy between measures of CFTR-mediated chloride conductance in expression systems and the sweat chloride values of patients.

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Year:  2001        PMID： 11448786     DOI： 10.1016/s0960-9822(01)00282-2

Source DB:  PubMed          Journal:  Curr Biol        ISSN： 0960-9822            Impact factor:   10.834


  4 in total

Review 1.  Cystic fibrosis-related oxidative stress and intestinal lipid disorders.

Authors:  Marie-Laure Kleme; Emile Levy
Journal:  Antioxid Redox Signal       Date:  2015-01-22       Impact factor: 8.401

2.  Tobramycin and bicarbonate synergise to kill planktonic Pseudomonas aeruginosa, but antagonise to promote biofilm survival.

Authors:  Karishma S Kaushik; Jake Stolhandske; Orrin Shindell; Hugh D Smyth; Vernita D Gordon
Journal:  NPJ Biofilms Microbiomes       Date:  2016-05-25       Impact factor: 7.290

Review 3.  Role of inflammation and oxidative stress in tissue damage associated with cystic fibrosis: CAPE as a future therapeutic strategy.

Authors:  Victor Emanuel Miranda Soares; Thiago Inácio Teixeira do Carmo; Fernanda Dos Anjos; Jonatha Wruck; Sarah Franco Vieira de Oliveira Maciel; Margarete Dulce Bagatini; Débora Tavares de Resende E Silva
Journal:  Mol Cell Biochem       Date:  2021-09-16       Impact factor: 3.396

Review 4.  Bicarbonate Transport in Cystic Fibrosis and Pancreatitis.

Authors:  Dora Angyal; Marcel J C Bijvelds; Marco J Bruno; Maikel P Peppelenbosch; Hugo R de Jonge
Journal:  Cells       Date:  2021-12-24       Impact factor: 6.600
  4 in total

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