| Literature DB >> 11447306 |
A Seed1, M P Love, J J McMurray.
Abstract
Both ET(A) selective and dual, ET(A/B), receptor antagonists have favourable short- and longer-term haemodynamic actions in patients with acute and chronic heart failure. Their effect on neurohumoral measures is not yet fully determined. Two moderately large, medium-duration studies have examined the effect of dual ET(A/B) receptor antagonists on clinical status, reaching conflicting conclusions. One large scale, long-term, morbidity mortality evaluation is underway with bosentan.Entities:
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Year: 2001 PMID： 11447306 DOI： 10.1023/a:1011408425878
Source DB: PubMed Journal: Heart Fail Rev ISSN： 1382-4147 Impact factor: 4.214