| Literature DB >> 11447201 |
Abstract
An understanding of the antigen presentation mechanisms that mediate induction of protective immune responses against malaria is essential for the development of successful immunization approaches. Here we show that dendritic cells presenting Plasmodium yoelii sporozoite antigens are able to activate specific CD4(+) and CD8(+) T cells and initiate protective immune responses against malaria in mice.Entities:
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Year: 2001 PMID: 11447201 PMCID: PMC98615 DOI: 10.1128/IAI.69.8.5173-5176.2001
Source DB: PubMed Journal: Infect Immun ISSN: 0019-9567 Impact factor: 3.441