Literature DB >> 114470

Intraperoxisomal and intramitochondrial localization, and assay of pyruvate (glyoxylate) aminotransferase from rat liver.

T Noguchi, Y Takada, Y Oota.   

Abstract

Pyruvate (glyoxylate) aminotransferase is found in the peroxisomal and mitochondrial matrices, and in soluble fractions of rat liver homogenates. Soluble activity is from broken peroxisomes. Differential solubility of the mitochondrial and peroxisomal enzymes in digitonin can be used to assay the two activities separately.

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Year:  1979        PMID： 114470     DOI： 10.1515/bchm2.1979.360.2.919

Source DB:  PubMed          Journal:  Hoppe Seylers Z Physiol Chem        ISSN： 0018-4888


  8 in total

Review 1.  Recent advances in the understanding, diagnosis and treatment of primary hyperoxaluria type 1.

Authors:  C J Danpure
Journal:  J Inherit Metab Dis       Date:  1989       Impact factor: 4.982

Review 2.  AGXT2: a promiscuous aminotransferase.

Authors:  Roman N Rodionov; Natalia Jarzebska; Norbert Weiss; Steven R Lentz
Journal:  Trends Pharmacol Sci       Date:  2014-10-13       Impact factor: 14.819

3.  Evolution of alanine:glyoxylate aminotransferase intracellular targeting: structural and functional analysis of the guinea pig gene.

Authors:  G M Birdsey; C J Danpure
Journal:  Biochem J       Date:  1998-04-01       Impact factor: 3.857

4.  Identification of mutations associated with peroxisome-to-mitochondrion mistargeting of alanine/glyoxylate aminotransferase in primary hyperoxaluria type 1.

Authors:  P E Purdue; Y Takada; C J Danpure
Journal:  J Cell Biol       Date:  1990-12       Impact factor: 10.539

5.  Quantitative immunocytochemical studies on differential induction of serine:pyruvate aminotransferase in mitochondria and peroxisomes of rat liver cells by administration of glucagon or di-(2-ethylhexyl)phthalate.

Authors:  S Yokota
Journal:  Histochemistry       Date:  1986

6.  Two mechanisms produce tissue-specific inhibition of fatty acid oxidation by oxfenicine.

Authors:  T W Stephens; A J Higgins; G A Cook; R A Harris
Journal:  Biochem J       Date:  1985-04-15       Impact factor: 3.857

7.  An enzyme trafficking defect in two patients with primary hyperoxaluria type 1: peroxisomal alanine/glyoxylate aminotransferase rerouted to mitochondria.

Authors:  C J Danpure; P J Cooper; P J Wise; P R Jennings
Journal:  J Cell Biol       Date:  1989-04       Impact factor: 10.539

8.  Mammalian alanine/glyoxylate aminotransferase 1 is imported into peroxisomes via the PTS1 translocation pathway. Increased degeneracy and context specificity of the mammalian PTS1 motif and implications for the peroxisome-to-mitochondrion mistargeting of AGT in primary hyperoxaluria type 1.

Authors:  A Motley; M J Lumb; P B Oatey; P R Jennings; P A De Zoysa; R J Wanders; H F Tabak; C J Danpure
Journal:  J Cell Biol       Date:  1995-10       Impact factor: 10.539
  8 in total

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