Literature DB >> 11446660

The nontreatment of childhood ITP (or "the art of medicine consists of amusing the patient until nature cures the disease").

P H Bolton-Maggs1, R Dickerhoff, A J Vora.   

Abstract

The management of childhood acute idiopathic thrombocytopenic purpura is controversial, with recent guidelines highlighting the lack of suitable evidence upon which to base management decisions. Three European centers have used an expectant policy and results over the past decade demonstrate that this is safe and convenient for the majority of children. Adequate parental education about the condition from an experienced specialist is essential, together with open access for children should they develop any problems. A clinical stratification of such patients must be incorporated into any future trials, together with quality of life assessment to discover the impact of restrictions on lifestyle, particularly in adolescents with chronic ITP who may need a different approach.

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Mesh:

Year:  2001        PMID: 11446660     DOI: 10.1055/s-2001-15256

Source DB:  PubMed          Journal:  Semin Thromb Hemost        ISSN: 0094-6176            Impact factor:   4.180


  4 in total

1.  Physician decision making in selection of second-line treatments in immune thrombocytopenia in children.

Authors:  Rachael F Grace; Jenny M Despotovic; Carolyn M Bennett; James B Bussel; Michelle Neier; Cindy Neunert; Shelley E Crary; Yves D Pastore; Robert J Klaassen; Jennifer A Rothman; Kerry Hege; Vicky R Breakey; Melissa J Rose; Kristin A Shimano; George R Buchanan; Amy Geddis; Kristina M Haley; Adonis Lorenzana; Alexis Thompson; Michael Jeng; Ellis J Neufeld; Travis Brown; Peter W Forbes; Michele P Lambert
Journal:  Am J Hematol       Date:  2018-05-06       Impact factor: 10.047

2.  Misdiagnosed thrombocytopenia in children and adolescents: analysis of the Pediatric and Adult Registry on Chronic ITP.

Authors:  Alexandra Schifferli; Andrea Heiri; Paul Imbach; Susanne Holzhauer; Markus G Seidel; Diane Nugent; Marc Michel; Thomas Kühne
Journal:  Blood Adv       Date:  2021-03-23

Review 3.  The Centenary of Immune Thrombocytopenia-Part 2: Revising Diagnostic and Therapeutic Approach.

Authors:  Rita Consolini; Giorgio Costagliola; Davide Spatafora
Journal:  Front Pediatr       Date:  2017-08-21       Impact factor: 3.418

4.  Evaluation of health related quality of life in children with immune thrombocytopenia with the PedsQL™ 4.0 Generic Core Scales: a study on behalf of the pays de Loire pediatric hematology network.

Authors:  Marion Strullu; Josué Rakotonjanahary; Eliane Tarral; Christophe Savagner; Caroline Thomas; Françoise Méchinaud; Yves Reguerre; Sylvaine Poignant; Arnaud Boutet; Joachim Bassil; Dominique Médinger; Emmanuel Quemener; Nancy L Young; Petronela Rachieru; Robert J Klaassen; Isabelle Pellier
Journal:  Health Qual Life Outcomes       Date:  2013-11-13       Impact factor: 3.186

  4 in total

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