| Literature DB >> 11445809 |
A G Kurkchubasche1, J A Panepinto, T F Tracy, G W Thurman, D R Ambruso.
Abstract
The case of an infant with multiple, rapidly progressive, soft-tissue infections is presented. Despite features suggesting a neutrophil disorder, results of screening tests of phagocyte function were normal. A novel, multifaceted leukocyte disorder-distinguished by defects in shape change, chemotaxis, ingestion, degranulation, superoxide anion production, and bactericidal activity-was established secondary to a defect in Rac2.Entities:
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Year: 2001 PMID： 11445809 DOI： 10.1067/mpd.2001.114718
Source DB: PubMed Journal: J Pediatr ISSN： 0022-3476 Impact factor: 4.406