Literature DB >> 11444586

Levofloxacin and warfarin interaction.

S L Ravnan1, C Locke.   

Abstract

Numerous case reports have documented an enhanced hypoprothrombinemic effect caused by an interaction between fluoroquinolones (most notably, ciprofloxacin) and warfarin sodium. Conflicting data exist regarding the clinical significance of this interaction. Two patients who had elevated international normalized ratios after receiving concurrent levofloxacin and warfarin sodium are described.

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Year:  2001        PMID： 11444586     DOI： 10.1592/phco.21.9.884.34559

Source DB:  PubMed          Journal:  Pharmacotherapy        ISSN： 0277-0008            Impact factor:   4.705


  5 in total

1.  Ezetimibe enhances and stabilizes anticoagulant effect of warfarin.

Authors:  Takehiro Hashikata; Minako Yamaoka-Tojo; Ryota Kakizaki; Teruyoshi Nemoto; Kazuhiro Fujiyoshi; Sayaka Namba; Lisa Kitasato; Takuya Hashimoto; Shunsuke Ishii; Ryo Kameda; Takao Shimohama; Taiki Tojo; Junya Ako
Journal:  Heart Vessels       Date:  2016-04-06       Impact factor: 2.037

2.  Impact of preemptive warfarin dose reduction on anticoagulation after initiation of trimethoprim-sulfamethoxazole or levofloxacin.

Authors:  Abrar Ahmed; John C Stephens; Carol A Kaus; William P Fay
Journal:  J Thromb Thrombolysis       Date:  2007-11-06       Impact factor: 2.300

3.  Adverse drug reactions related to the use of fluoroquinolone antimicrobials: an analysis of spontaneous reports and fluoroquinolone consumption data from three italian regions.

Authors:  Roberto Leone; Mauro Venegoni; Domenico Motola; Ugo Moretti; Valentina Piazzetta; Alfredo Cocci; Domenico Resi; Federico Mozzo; Giampaolo Velo; Liliana Burzilleri; Nicola Montanaro; Anita Conforti
Journal:  Drug Saf       Date:  2003       Impact factor: 5.606

4.  Retrospective assessment of potential interaction between levofloxacin and warfarin.

Authors:  Gabriel Mercadal Orfila; Berta Gracia García; Elisabet Leiva Badosa; María Perayre Badía; Concepción Reynaldo Martínez; Ramón Jodar Masanés
Journal:  Pharm World Sci       Date:  2008-12-06

5.  Anticoagulant-induced changes on antibiotic concentrations in the serum and bones.

Authors:  A Kotsiou; E Diamanti; A Potamianou; H Parara; J Vovou; C Perisanidis; C Tes; C Tesseromatis
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2008 Jul-Sep       Impact factor: 2.441
  5 in total

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