Literature DB >> 11444394

Functional genomics of the murine immune system.

H E Ruley1.   

Abstract

The mouse and human genome sequences provide new opportunities to characterize mammalian gene functions on a genome-wide level. Toward this end, we have developed strategies for tagged-sequence mutagenesis in mice. Tagged-sequence mutagenesis has been used first, to analyze genes implicated in posttranscriptional gene regulation, and second, to identify genes important in immune cell development and function.

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Year:  2001        PMID： 11444394     DOI： 10.1385/IR:23:2-3:289

Source DB:  PubMed          Journal:  Immunol Res        ISSN： 0257-277X            Impact factor:   2.829


  55 in total

1.  RET: a poly A-trap retrovirus vector for reversible disruption and expression monitoring of genes in living cells.

Authors:  Y Ishida; P Leder
Journal:  Nucleic Acids Res       Date:  1999-12-15       Impact factor: 16.971

2.  Establishment of a gene-trap sequence tag library to generate mutant mice from embryonic stem cells.

Authors:  M V Wiles; F Vauti; J Otte; E M Füchtbauer; P Ruiz; A Füchtbauer; H H Arnold; H Lehrach; T Metz; H von Melchner; W Wurst
Journal:  Nat Genet       Date:  2000-01       Impact factor: 38.330

3.  Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice.

Authors:  G Friedrich; P Soriano
Journal:  Genes Dev       Date:  1991-09       Impact factor: 11.361

4.  Transcriptional specificity of the pluripotent embryonic stem cell.

Authors:  C A Scherer; J Chen; A Nachabeh; N Hopkins; H E Ruley
Journal:  Cell Growth Differ       Date:  1996-10

5.  Disruption and sequence identification of 2,000 genes in mouse embryonic stem cells.

Authors:  B P Zambrowicz; G A Friedrich; E C Buxton; S L Lilleberg; C Person; A T Sands
Journal:  Nature       Date:  1998-04-09       Impact factor: 49.962

Review 6.  Targeting the mouse genome: a compendium of knockouts (Part II)

Authors:  E P Brandon; R L Idzerda; G S McKnight
Journal:  Curr Biol       Date:  1995-07-01       Impact factor: 10.834

7.  Smad7-dependent regulation of heme oxygenase-1 by transforming growth factor-beta in human renal epithelial cells.

Authors:  N Hill-Kapturczak; L Truong; V Thamilselvan; G A Visner; H S Nick; A Agarwal
Journal:  J Biol Chem       Date:  2000-12-29       Impact factor: 5.157

8.  Retrovirus promoter-trap vector to induce lacZ gene fusions in mammalian cells.

Authors:  S Reddy; J V DeGregori; H von Melchner; H E Ruley
Journal:  J Virol       Date:  1991-03       Impact factor: 5.103

Review 9.  Tumor necrosis factor: a pleiotropic cytokine and therapeutic target.

Authors:  K J Tracey; A Cerami
Journal:  Annu Rev Med       Date:  1994       Impact factor: 13.739

10.  Selective disruption of genes expressed in totipotent embryonal stem cells.

Authors:  H von Melchner; J V DeGregori; H Rayburn; S Reddy; C Friedel; H E Ruley
Journal:  Genes Dev       Date:  1992-06       Impact factor: 11.361
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  1 in total

Review 1.  Signaling advances from immunogenetics to immunogenomics.

Authors:  Mark Boothby
Journal:  Genome Biol       Date:  2003-11-19       Impact factor: 13.583
  1 in total

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