Literature DB >> 11443431

Laparoscopic pancreatectomy for persistent hyperinsulinemic hypoglycemia of infancy.

M L Blakely1, T E Lobe, J Cohen, G A Burghen.   

Abstract

BACKGROUND: A 4-week-old male infant (4.9 kg) with persistent hyperinsulinemic hypoglycemia of infancy (PHHI) underwent a laparoscopic pancreatectomy to evaluate its feasibility. Preoperative medications included diazoxide and glucagon to maintain adequate blood glucose levels.
METHODS: Laparoscopic pancreatectomy was performed using a 5-mm cannula at the umbilicus, external fixation, transcutaneous suture-assisted gastric retraction to expose the lesser sac, and three additional 3.5-mm cannula sites. The pancreas was resected from the splenic hilum to the mesenteric vessels. The splenic vein was dissected from the under surface of the pancreas using electrocautery, and the spleen was easily preserved. Surgery time was 75 min, and minimal blood loss occurred.
RESULTS: The child required no narcotic medication and tolerated a regular diet immediately after surgery. Serum glucose levels did decrease postoperatively, and the child required diazoxide, dextrose infusion, glucagon, and octreotide. On postoperative day 7, the child underwent an open near-total pancreatectomy, after which he remained asymptomatic. Essentially no scarring was found in the lesser sac, and the remaining pancreatic remnant was resected without difficulty.
CONCLUSIONS: Laparoscopic pancreatectomy can be performed safely, even in a newborn patient, without prolonged operative time or unnecessary risk. The technique using external fixation and transcutaneous suture-assisted gastric retraction provides excellent exposure to the pancreas and lesser sac. In patients with PHHI, in whom reoperative additional pancreatectomy is very likely, this technique is the ideal initial surgical approach.

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Year:  2001        PMID: 11443431     DOI: 10.1007/s004640040031

Source DB:  PubMed          Journal:  Surg Endosc        ISSN: 0930-2794            Impact factor:   4.584


  7 in total

1.  Laparoscopic identification and removal of focal lesions in persistent hyperinsulinemic hypoglycemia of infancy.

Authors:  N M A Bax; D C van der Zee; M de Vroede; M Jansen; J Nikkels
Journal:  Surg Endosc       Date:  2003-05       Impact factor: 4.584

2.  Laparoscopic distal pancreatectomy for Frantz's tumor in a child.

Authors:  E Carricaburu; G Enezian; A Bonnard; D Berrebi; N Belarbi; O Huot; Y Aigrain; P de Lagausie
Journal:  Surg Endosc       Date:  2003-11-06       Impact factor: 4.584

Review 3.  Advances in the diagnosis and management of hyperinsulinemic hypoglycemia.

Authors:  Ritika R Kapoor; Chela James; Khalid Hussain
Journal:  Nat Clin Pract Endocrinol Metab       Date:  2009-02

4.  Clinical practice guidelines for congenital hyperinsulinism.

Authors:  Tohru Yorifuji; Reiko Horikawa; Tomonobu Hasegawa; Masanori Adachi; Shun Soneda; Masanori Minagawa; Shinobu Ida; Takeo Yonekura; Yoshiaki Kinoshita; Yutaka Kanamori; Hiroaki Kitagawa; Masato Shinkai; Hideyuki Sasaki; Masaki Nio
Journal:  Clin Pediatr Endocrinol       Date:  2017-07-27

Review 5.  Somatostatin analogues for the treatment of hyperinsulinaemic hypoglycaemia.

Authors:  Basma Haris; Saras Saraswathi; Khalid Hussain
Journal:  Ther Adv Endocrinol Metab       Date:  2020-12-02       Impact factor: 3.565

6.  Laparoscopic Surgery for Focal-Form Congenital Hyperinsulinism Located in Pancreatic Head.

Authors:  Zhe Wen; Jieqin Wang; Qifeng Liang; Xiaopan Chang; Wen Zhang; Huilin Niu; Qiao He
Journal:  Front Pediatr       Date:  2022-07-19       Impact factor: 3.569

Review 7.  Laparoscopic pancreatic resection: the past, present, and future.

Authors:  Kyoichi Takaori; Nobuhiko Tanigawa
Journal:  Surg Today       Date:  2007-06-26       Impact factor: 2.540

  7 in total

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