Literature DB >> 11443229

Molecular physiology of renal p-aminohippurate secretion.

G Burckhardt1, A Bahn, N A Wolff.   

Abstract

Renal proximal tubules secrete various organic anions, including drugs and p-aminohippurate (PAH). Uptake of PAH from blood into tubule cells occurs by exchange with intracellular alpha-ketoglutarate and is mediated by the organic anion transporter 1. PAH exit into tubule lumen is species specific and may involve ATP-independent and -dependent transporters.

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Year:  2001        PMID： 11443229     DOI： 10.1152/physiologyonline.2001.16.3.114

Source DB:  PubMed          Journal:  News Physiol Sci        ISSN： 0886-1714


  13 in total

Review 1.  Physiology, structure, and regulation of the cloned organic anion transporters.

Authors:  C Srimaroeng; J L Perry; J B Pritchard
Journal:  Xenobiotica       Date:  2008-07       Impact factor: 1.908

2.  Dynamics of Organic Anion Transporter-Mediated Tubular Secretion during Postnatal Human Kidney Development and Maturation.

Authors:  Jeremiah D Momper; Jin Yang; Mary Gockenbach; Florin Vaida; Sanjay K Nigam
Journal:  Clin J Am Soc Nephrol       Date:  2019-03-18       Impact factor: 8.237

3.  Torsemide renal clearance and genetic variation in luminal and basolateral organic anion transporters.

Authors:  Stefan V Vormfelde; Markus Schirmer; Yohannes Hagos; Mohammad R Toliat; Sabine Engelhardt; Ingolf Meineke; Gerhard Burckhardt; Peter Nürnberg; Jürgen Brockmöller
Journal:  Br J Clin Pharmacol       Date:  2006-09       Impact factor: 4.335

4.  Presence of organic anion transporters 3 (OAT3) and 4 (OAT4) in human adrenocortical cells.

Authors:  Abdul R Asif; Jürgen Steffgen; Maria Metten; R Willi Grunewald; Gerhard A Müller; Andrew Bahn; Gerhard Burckhardt; Yohannes Hagos
Journal:  Pflugers Arch       Date:  2004-12-10       Impact factor: 3.657

5.  The flounder organic anion transporter fOat has sequence, function, and substrate specificity similarity to both mammalian Oat1 and Oat3.

Authors:  Amy G Aslamkhan; Deborah M Thompson; Jennifer L Perry; Kelly Bleasby; Natascha A Wolff; Scott Barros; David S Miller; John B Pritchard
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2006-07-20       Impact factor: 3.619

6.  Interactions of stevioside and steviol with renal organic anion transporters in S2 cells and mouse renal cortical slices.

Authors:  Chutima Srimaroeng; Promsuk Jutabha; John B Pritchard; Hitoshi Endou; Varanuj Chatsudthipong
Journal:  Pharm Res       Date:  2005-06-08       Impact factor: 4.200

7.  Role of rat organic anion transporter 3 (Oat3) in the renal basolateral transport of glutathione.

Authors:  Lawrence H Lash; David A Putt; Feng Xu; Larry H Matherly
Journal:  Chem Biol Interact       Date:  2007-07-19       Impact factor: 5.192

8.  Basolateral localization of flounder Na+-dicarboxylate cotransporter (fNaDC-3) in the kidney of Pleuronectes americanus.

Authors:  Hartmut Hentschel; Birgitta C Burckhardt; Beate Schölermann; Lars Kühne; Gerhard Burckhardt; Jürgen Steffgen
Journal:  Pflugers Arch       Date:  2003-05-21       Impact factor: 3.657

9.  Organic anion transporter 3 contributes to the regulation of blood pressure.

Authors:  Volker Vallon; Satish A Eraly; William R Wikoff; Timo Rieg; Gregory Kaler; David M Truong; Sun-Young Ahn; Nitish R Mahapatra; Sushil K Mahata; Jon A Gangoiti; Wei Wu; Bruce A Barshop; Gary Siuzdak; Sanjay K Nigam
Journal:  J Am Soc Nephrol       Date:  2008-05-28       Impact factor: 10.121

Review 10.  Incorporating Ontogeny in Physiologically Based Pharmacokinetic Modeling to Improve Pediatric Drug Development: What We Know About Developmental Changes in Membrane Transporters.

Authors:  Kit Wun Kathy Cheung; Bianca D van Groen; Gilbert J Burckart; Lei Zhang; Saskia N de Wildt; Shiew-Mei Huang
Journal:  J Clin Pharmacol       Date:  2019-09       Impact factor: 3.126
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