Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Intracellular Ca2+ release sparks atrial pacemaker activity.

Literature DB >> 11443225

Intracellular Ca2+ release sparks atrial pacemaker activity.

Abstract

Electrical excitation of the mammalian heart originates from specialized pacemaker cells in the right atrium. Pacemaker activity depends on multiple ion channels and transport mechanisms that reside primarily within the plasma membrane. However, recent evidence indicates that intracellular Ca2+ release from the sarcoplasmic reticulum also contributes importantly to atrial pacemaker function.

Entities: Chemical Species

Mesh：

Substances：

Year: 2001 PMID： 11443225 DOI： 10.1152/physiologyonline.2001.16.3.101

Source DB: PubMed Journal: News Physiol Sci ISSN： 0886-1714

Keyword Cloud
Cited

26 in total

Review 1. Regulation of cardiac excitation-contraction coupling by action potential repolarization: role of the transient outward potassium current (I(to)).

Authors: Rajan Sah; Rafael J Ramirez; Gavin Y Oudit; Dominica Gidrewicz; Maria G Trivieri; Carsten Zobel; Peter H Backx
Journal: J Physiol Date: 2003-01-01 Impact factor: 5.182

Review 2. Low-voltage-activated ("T-Type") calcium channels in review.

Authors: Anne Marie R Yunker; Maureen W McEnery
Journal: J Bioenerg Biomembr Date: 2003-12 Impact factor: 2.945

3. Modulation of local Ca2+ release sites by rapid fluid puffing in rat atrial myocytes.

Authors: Sun-Hee Woo; Tim Risius; Martin Morad
Journal: Cell Calcium Date: 2006-11-07 Impact factor: 6.817

4. Mechanisms of intrinsic beating variability in cardiac cell cultures and model pacemaker networks.

Authors: Julien G C Ponard; Aleksandar A Kondratyev; Jan P Kucera
Journal: Biophys J Date: 2007-02-26 Impact factor: 4.033

5. Regulation of calcium clock-mediated pacemaking by inositol-1,4,5-trisphosphate receptors in mouse sinoatrial nodal cells.

Authors: Nidhi Kapoor; Andrew Tran; Jeanney Kang; Rui Zhang; Kenneth D Philipson; Joshua I Goldhaber
Journal: J Physiol Date: 2015-05-26 Impact factor: 5.182

Intracellular Ca2+ release sparks atrial pacemaker activity.

Review 1. Regulation of cardiac excitation-contraction coupling by action potential repolarization: role of the transient outward potassium current (I(to)).

Review 2. Low-voltage-activated ("T-Type") calcium channels in review.

3. Modulation of local Ca2+ release sites by rapid fluid puffing in rat atrial myocytes.

4. Mechanisms of intrinsic beating variability in cardiac cell cultures and model pacemaker networks.

5. Regulation of calcium clock-mediated pacemaking by inositol-1,4,5-trisphosphate receptors in mouse sinoatrial nodal cells.

6. Differential effects of organic calcium-channel blockers on diastolic SR calcium-handling in the frog heart.

Review 7. The funny current: cellular basis for the control of heart rate.

8. Initiation and propagation of ectopic waves: insights from an in vitro model of ischemia-reperfusion injury.

9. Cryoablation of stellate ganglia and atrial arrhythmia in ambulatory dogs with pacing-induced heart failure.

Review 10. T-type channels in the sino-atrial and atrioventricular pacemaker mechanism.