Literature DB >> 11442851

Antifungal activity of histatin-5 against non-albicans Candida species.

H Nikawa1, C Jin, H Fukushima, S Makihira, T Hamada.   

Abstract

Fungicidal effects of histatin-5 against 26 oral isolates belonging to 5 non-albicans Candida species were examined. Fifty microM of histatin-5 killed more than 95% of Candida tropicalis and Candida guilliermondii isolates and more than 90% of Candida parapsilosis and Candida krusei. However, Candida glabrata was less sensitive to the peptide (mean 62.9%). Our results, taken together, demonstrated that histatin-5 possessed the fungicidal activity against Candida species other than C. glabrata.

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Year:  2001        PMID: 11442851     DOI: 10.1034/j.1399-302x.2001.160409.x

Source DB:  PubMed          Journal:  Oral Microbiol Immunol        ISSN: 0902-0055


  10 in total

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Journal:  Antimicrob Agents Chemother       Date:  2016-07-22       Impact factor: 5.191

2.  Development and In Vivo Evaluation of a Novel Histatin-5 Bioadhesive Hydrogel Formulation against Oral Candidiasis.

Authors:  Eric F Kong; Christina Tsui; Heather Boyce; Ahmed Ibrahim; Stephen W Hoag; Amy J Karlsson; Timothy F Meiller; Mary Ann Jabra-Rizk
Journal:  Antimicrob Agents Chemother       Date:  2015-11-23       Impact factor: 5.191

3.  Susceptibility of Candida dubliniensis to salivary histatin 3.

Authors:  Deirdre H Fitzgerald; David C Coleman; Brian C O'Connell
Journal:  Antimicrob Agents Chemother       Date:  2003-01       Impact factor: 5.191

4.  Impaired Histatin-5 Levels and Salivary Antimicrobial Activity against C. albicans in HIV Infected Individuals.

Authors:  Shariq A Khan; Paul L Fidel; Awdah Al Thunayyan; Sharon Varlotta; Timothy F Meiller; Mary Ann Jabra-Rizk
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5.  Salivary statherin peptide-binding epitopes of commensal and potentially infectious Actinomyces spp. delineated by a hybrid peptide construct.

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Review 6.  Antimicrobial peptides in the oral environment: expression and function in health and disease.

Authors:  Beverly A Dale; L Page Fredericks
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Review 7.  Antimicrobial Peptides with Anti-Candida Activity.

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Journal:  Int J Mol Sci       Date:  2022-08-17       Impact factor: 6.208

8.  The antimicrobial peptide histatin-5 causes a spatially restricted disruption on the Candida albicans surface, allowing rapid entry of the peptide into the cytoplasm.

Authors:  A Brian Mochon; Haoping Liu
Journal:  PLoS Pathog       Date:  2008-10-31       Impact factor: 6.823

9.  A study on β-defensin-2 and histatin-5 as a diagnostic marker of early childhood caries progression.

Authors:  Anna Jurczak; Dorota Kościelniak; Monika Papież; Palina Vyhouskaya; Wirginia Krzyściak
Journal:  Biol Res       Date:  2015-10-31       Impact factor: 5.612

Review 10.  Antimicrobial Peptides: a New Frontier in Antifungal Therapy.

Authors:  Giuseppe Buda De Cesare; Shane A Cristy; Danielle A Garsin; Michael C Lorenz
Journal:  mBio       Date:  2020-11-03       Impact factor: 7.867

  10 in total

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