Literature DB >> 11441285

Giant malignant mesenchymoma of the spermatic cord with bidirectional differentiation.

R Paul1, H Leyh, M Hillemanns, H Höfler, R Hartung.   

Abstract

BACKGROUND: Spermatic cord neoplasms are a rare tumor entity and, moreover, of benign behavior. Malignant tumors of the spermatic cord are mostly of mesenchymal origin. We present the unusual case of a giant malignant mesenchymoma of the spermatic cord with bidirectional differentiation into a liposarcoma and a leiomyosarcoma. CASE REPORT: A 84-year-old male patient presented with a scrotal mass on the left side which was observed growing since 1 year and misdiagnosed as scrotal hernia or testicular hydrocele. Ultrasound and computed tomography demonstrated a solid tumor suggesting a spermatic cord tumor. The patient underwent hemiscrotectomy, and the histological examination of the 2,500-gram specimen revealed a malignant mesenchymoma originating from the spermatic cord with two distinct histopathological compartments of liposarcoma and leiomyosarcoma. Because an adjuvant therapy protocol is of questionable effect and because of the patient's age no further therapy was applied. The patient was closely followed and is now, 5 years after surgery, still free of disease.
CONCLUSION: Even in older patients, scrotal masses should be considered malignant tumors as long as no benign diagnosis has been proven. Although malignant mesenchymomas are rare tumors with poor prognosis, in selected cases even large tumor masses, as presented, can be cured by surgery. Copyright 2001 S. Karger GmbH, Freiburg

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Mesh:

Year:  2001        PMID: 11441285     DOI: 10.1159/000050286

Source DB:  PubMed          Journal:  Onkologie        ISSN: 0378-584X


  2 in total

Review 1.  Malignant mesenchymal tumor with leiomyosarcoma, rhabdomyosarcoma, chondrosarcoma, and osteosarcoma differentiation: case report and literature review.

Authors:  Yao-Feng Li; Cheng-Ping Yu; Seng-Tang Wu; Ming-Shen Dai; Herng-Sheng Lee
Journal:  Diagn Pathol       Date:  2011-04-15       Impact factor: 2.644

2.  Commentary on "A Case of Paratesticular Leiomyosarcoma Successfully Treated with Orchiectomy and Chemotherapy".

Authors:  Edoardo Virgilio; Stefania Uccini; Paolo Marchetti; Paolo Mercantini
Journal:  Cancer Res Treat       Date:  2015-12-02       Impact factor: 4.679

  2 in total

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