| Literature DB >> 1144065 |
A Caputo, G Zupi, A Clanciulli.
Abstract
By means of DNA-cellulose chromatography an enzyme with endonucleolytic activity has been isolated from nuclear acidic protein fraction of mammalian cells. The main active fraction, eluted at 0.7 M NaCl, effects the velocity sedimentation of UV-irradiated and alkylated DNA, resulting in a decrease of the molecular weight. The fraction is completely inactive using native as well as heat-denatured DNA.Entities:
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Year: 1975 PMID： 1144065 PMCID： PMC343477 DOI： 10.1093/nar/2.6.905
Source DB: PubMed Journal: Nucleic Acids Res ISSN： 0305-1048 Impact factor: 16.971