Literature DB >> 11439489

Modeling the output ratio in air for megavoltage photon beams.

T C Zhu1, B E Bjärngard, Y Xiao, C J Yang.   

Abstract

The output ratio in air, OR, for a high-energy x-ray beam describes how the incident central axis photon fluence varies with collimator setting. For field sizes larger than 3 x 3 cm2, its variation is caused by the scatter of photons in structures in the accelerator head (primarily the flattening filter and the wedge, if one is used) and by the backscatter of radiation into the monitor ionization chamber. The objective of this study was to evaluate the use of an analytical function to parametrize OR for square collimator setting c: OR = (1 + a1.c).[1 + a2.erf(c/lambda)2].H0. For open beams, these parameters can be attributed to explicit physical meanings within the systematical uncertainty of the model: a1 accounts for backscatter into the monitor, a2 is the maximum scatter-to-primary ratio for head-scattered photons, and lambda represents the effective width of the "source" of head-scatter photons. H0 is a constant that sets OR = 1 for c = 10 cm. This formula also fits OR for wedge beams and a Co-60 unit, although the fitting parameters lose their physical interpretations. To calculate the output ratio for a rectangular field, cx x cy, an equivalent square can be used: c = (1 + k).cy x cx/(k.cx + cy), where k is a constant. The study included a number of different accelerators and a cobalt-60 unit. The fits for square fields agreed with measurements with a standard deviation (SD) of less than 0.5%. Using k = lx.(f - ly)/ly.(f - lx), where lx and ly are the source-to-collimator distances and f is the source-to-detector distance, measurements and calculations agreed within a SD of 0.7% for rectangular fields. Sufficient data for the three parameters are presented to suggest constraints that can be used for quality assurance of the measured output ratio in air.

Entities:  

Mesh:

Year:  2001        PMID: 11439489     DOI: 10.1118/1.1376639

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  9 in total

1.  A method for determination of the absorption and scattering properties interstitially in turbid media.

Authors:  Andreea Dimofte; Jarod C Finlay; Timothy C Zhu
Journal:  Phys Med Biol       Date:  2005-05-05       Impact factor: 3.609

2.  Experimental evaluations of head scatter factor calculation by use of a Gaussian function.

Authors:  Ryoichi Notake; Yukishige Kyuuma; Kouji Sasamori; Makoto Sagawa; Yasushi Annaka; Hidetoshi Saitoh; Hitoshi Shibuya
Journal:  Radiol Phys Technol       Date:  2013-12-10

3.  A convolution/superposition method using primary and scatter dose kernels formed for energy bins of X-ray spectra reconstructed as a function of off-axis distance: a theoretical study on 10-MV X-ray dose calculations in thorax-like phantoms.

Authors:  Akira Iwasaki; Shigenobu Kimura; Kohji Sutoh; Kazuo Kamimura; Makoto Sasamori; Fumio Komai; Morio Seino; Singo Terashima; Mamoru Kubota; Junichi Hirota; Yoichiro Hosokawa
Journal:  Radiol Phys Technol       Date:  2011-06-15

4.  Prostate PDT dosimetry.

Authors:  Timothy C Zhu; Jarod C Finlay
Journal:  Photodiagnosis Photodyn Ther       Date:  2006-10-19       Impact factor: 3.631

5.  Optimization of light sources for prostate photodynamic therapy.

Authors:  Martin D Altschuler; Timothy C Zhu; Jun Li; Stephen M Hahn
Journal:  Proc SPIE Int Soc Opt Eng       Date:  2005-04-22

6.  In-vivo light dosimetry of interstitial PDT of human prostate.

Authors:  Timothy C Zhu; Jun Li; Jarod C Finlay; Andreea Dimofte; Diana Stripp; Bruce S Malkowicz; Stephen M Hahn
Journal:  Proc SPIE Int Soc Opt Eng       Date:  2006-01-21

7.  Optical properties of human prostate at 732 nm measured in mediated photodynamic therapy.

Authors:  Timothy C Zhu; Andreea Dimofte; Jarod C Finlay; Diana Stripp; Theresa Busch; Jeremy Miles; Richard Whittington; S Bruce Malkowicz; Zelig Tochner; Eli Glatstein; Stephen M Hahn
Journal:  Photochem Photobiol       Date:  2005 Jan-Feb       Impact factor: 3.421

8.  Determination of the distribution of light, optical properties, drug concentration, and tissue oxygenation in-vivo in human prostate during motexafin lutetium-mediated photodynamic therapy.

Authors:  Timothy C Zhu; Jarod C Finlay; Stephen M Hahn
Journal:  J Photochem Photobiol B       Date:  2004-12-02       Impact factor: 6.252

9.  Optimized interstitial PDT prostate treatment planning with the Cimmino feasibility algorithm.

Authors:  Martin D Altschuler; Timothy C Zhu; Jun Li; Stephen M Hahn
Journal:  Med Phys       Date:  2005-12       Impact factor: 4.071

  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.