Literature DB >> 11437409

Tcf-3 expression and beta-catenin mediated transcriptional activation in aggressive fibromatosis (desmoid tumour).

S Tejpar1, C Li, C Yu, R Poon, H Denys, R Sciot, E Van Cutsem, J J Cassiman, B A Alman.   

Abstract

Aggressive fibromatosis harbours mutations resulting in beta-catenin protein stabilization. Primary cell cultures demonstrate constitutive tcf activation in aggressive fibromatosis. Expression and co-immunoprecipitation studies suggest that beta-catenin binds and activates tcf-3 in this tumour. This is the first demonstration of tcf-3 activation by beta-catenin stabilization in a human neoplastic process. Copyright 2001 Cancer Research Campaign.

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Year:  2001        PMID： 11437409      PMCID： PMC2363921          DOI： 10.1054/bjoc.2001.1857

Source DB:  PubMed          Journal:  Br J Cancer        ISSN： 0007-0920            Impact factor:   7.640


  20 in total

1.  Increased beta-catenin protein and somatic APC mutations in sporadic aggressive fibromatoses (desmoid tumors).

Authors:  B A Alman; C Li; M E Pajerski; S Diaz-Cano; H J Wolfe
Journal:  Am J Pathol       Date:  1997-08       Impact factor: 4.307

2.  Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells.

Authors:  O Tetsu; F McCormick
Journal:  Nature       Date:  1999-04-01       Impact factor: 49.962

3.  A common human skin tumour is caused by activating mutations in beta-catenin.

Authors:  E F Chan; U Gat; J M McNiff; E Fuchs
Journal:  Nat Genet       Date:  1999-04       Impact factor: 38.330

4.  Adenomatous polyposis coli gene mutation alters proliferation through its beta-catenin-regulatory function in aggressive fibromatosis (desmoid tumor).

Authors:  C Li; B Bapat; B A Alman
Journal:  Am J Pathol       Date:  1998-09       Impact factor: 4.307

5.  Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma.

Authors:  V Korinek; N Barker; P J Morin; D van Wichen; R de Weger; K W Kinzler; B Vogelstein; H Clevers
Journal:  Science       Date:  1997-03-21       Impact factor: 47.728

6.  Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC.

Authors:  P J Morin; A B Sparks; V Korinek; N Barker; H Clevers; B Vogelstein; K W Kinzler
Journal:  Science       Date:  1997-03-21       Impact factor: 47.728

7.  Deletion of an amino-terminal sequence beta-catenin in vivo and promotes hyperphosporylation of the adenomatous polyposis coli tumor suppressor protein.

Authors:  S Munemitsu; I Albert; B Rubinfeld; P Polakis
Journal:  Mol Cell Biol       Date:  1996-08       Impact factor: 4.272

8.  Aggressive fibromatosis (desmoid tumor) is a monoclonal disorder.

Authors:  B A Alman; M E Pajerski; S Diaz-Cano; K Corboy; H J Wolfe
Journal:  Diagn Mol Pathol       Date:  1997-04

9.  Lymphoid enhancer factor 1 directs hair follicle patterning and epithelial cell fate.

Authors:  P Zhou; C Byrne; J Jacobs; E Fuchs
Journal:  Genes Dev       Date:  1995-03-15       Impact factor: 11.361

10.  Restricted high level expression of Tcf-4 protein in intestinal and mammary gland epithelium.

Authors:  N Barker; G Huls; V Korinek; H Clevers
Journal:  Am J Pathol       Date:  1999-01       Impact factor: 4.307
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  13 in total

1.  Galectin-1 is silenced by promoter hypermethylation and its re-expression induces apoptosis in human colorectal cancer cells.

Authors:  Arun Satelli; U Subrahmanyeswara Rao
Journal:  Cancer Lett       Date:  2010-11-30       Impact factor: 8.679

Review 2.  The enigma of desmoid tumors.

Authors:  Scott Okuno
Journal:  Curr Treat Options Oncol       Date:  2006-11

3.  An association between the 4G polymorphism in the PAI-1 promoter and the development of aggressive fibromatosis (desmoid tumor) in familial adenomatous polyposis patients.

Authors:  Catherine F Li; Robert Y Wei; Frank Baliko; Bharati Bapat; Benjamin A Alman
Journal:  Fam Cancer       Date:  2007       Impact factor: 2.375

4.  A functional screen in human cells identifies UBF2 as an RNA polymerase II transcription factor that enhances the beta-catenin signaling pathway.

Authors:  Dorre A Grueneberg; Lourdes Pablo; Kang-Quan Hu; Paul August; Zhigang Weng; Jacqueline Papkoff
Journal:  Mol Cell Biol       Date:  2003-06       Impact factor: 4.272

5.  Targeting stem cell behavior in desmoid tumors (aggressive fibromatosis) by inhibiting hedgehog signaling.

Authors:  Ronak Ghanbari-Azarnier; Shingo Sato; Qingxia Wei; Mushriq Al-Jazrawe; Benjamin A Alman
Journal:  Neoplasia       Date:  2013-07       Impact factor: 5.715

6.  Beta-catenin is a mediator of the response of fibroblasts to irradiation.

Authors:  Ananta Gurung; Faisal Uddin; Richard P Hill; Peter C Ferguson; Benjamin A Alman
Journal:  Am J Pathol       Date:  2008-11-26       Impact factor: 4.307

7.  A high throughput screen identifies Nefopam as targeting cell proliferation in β-catenin driven neoplastic and reactive fibroproliferative disorders.

Authors:  Raymond Poon; Helen Hong; Xin Wei; James Pan; Benjamin A Alman
Journal:  PLoS One       Date:  2012-05-30       Impact factor: 3.240

8.  Familial adenomatous polyposis-associated desmoids display significantly more genetic changes than sporadic desmoids.

Authors:  Els Robanus-Maandag; Cathy Bosch; Saeid Amini-Nik; Jeroen Knijnenburg; Karoly Szuhai; Pascale Cervera; Raymond Poon; Diana Eccles; Paolo Radice; Marco Giovannini; Benjamin A Alman; Sabine Tejpar; Peter Devilee; Riccardo Fodde
Journal:  PLoS One       Date:  2011-09-09       Impact factor: 3.240

9.  Human sterile alpha motif domain 9, a novel gene identified as down-regulated in aggressive fibromatosis, is absent in the mouse.

Authors:  Catherine F Li; Jeffrey R MacDonald; Robert Y Wei; Jocelyn Ray; Kimberly Lau; Christopher Kandel; Rachel Koffman; Sherilyn Bell; Stephen W Scherer; Benjamin A Alman
Journal:  BMC Genomics       Date:  2007-04-03       Impact factor: 3.969

10.  Beta-catenin and transforming growth factor beta have distinct roles regulating fibroblast cell motility and the induction of collagen lattice contraction.

Authors:  Raymond Poon; Saeid Amini Nik; Jessica Ahn; Laura Slade; Benjamin A Alman
Journal:  BMC Cell Biol       Date:  2009-05-11       Impact factor: 4.241
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